ArticleThoracic cancer2017
Risk factors associated with treatment refusal in lung cancer.
Article in Thoracic cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed.
- Best supportive care in stage I-III non-small cell lung cancer: survival by reason for curative treatment omission in a real-world study population.Translational lung cancer research · 2026Article
- Inequalities in receipt of specialized consultation and treatment by material resources among stage IV non-small cell lung cancer patients: a population-based cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Confronting nihilism and stigma in lung cancer: The nurse practitioner's role in restoring hope and trust.Journal of the American Association of Nurse Practitioners · 2026Article
- Exploring behavioural motivations of treatment refusal in cancer: a Q-methodological approach.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Disparities in inpatient treatment and expenditures among lung cancer patients under tiered social health insurance: a population-based study in China.International journal for equity in health · 2025Article
- Role of Nanoformulations in the Treatment of Lung Cancer.Recent patents on nanotechnology · 2025Review
- Optimizing lung cancer surgery in the elderly: sublobar resection versus lobectomy for early-stage non-small cell lung cancer patients aged 80 and above.Discover oncology · 2024Article
- Building Frontline Capability for Shared Decision-Making (SDM) in a Major Academic Oncology Center Caring for People With Non-Small Cell Lung Cancer: Performance Outcomes of a SDM Simulation Training Program.The Permanente journal · 2024Article
- Declination of Treatment, Racial and Ethnic Disparity, and Overall Survival in US Patients With Breast Cancer.JAMA network open · 2024Article
- A population-based propensity score matching analysis of risk factors and the impact on survival associated with refusal of cancer-directed surgery in patients with prostate cancer.Scientific reports · 2024Article
- Determinants of Patient Refusal of Postoperative Radiation Therapy in Sinonasal Squamous Cell Carcinoma.Journal of neurological surgery. Part B, Skull base · 2023Article
- Factors Associated with the Decision to Decline Chemotherapy in Metastatic Non-Small Cell Lung Cancer.Cancers · 2023Article
- How do cancer patients refuse treatment? A grounded theory study.BMC palliative care · 2023Article
- Older adults' refusal speech act in cognitive assessment: A multimodal pragmatic perspective.Frontiers in psychology · 2023Article
- Women with short survival after diagnosis of metastatic breast cancer: a population-based registry study.Breast cancer research and treatment · 2022Article
- Article
- Fatalism, distrust, and breast cancer treatment refusal in Ghana.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2022Article
- Factors Associated with Refusal or Discontinuation of Treatment in Patients with Bladder Cancer: A Cohort Population-Based Study in Taiwan.International journal of environmental research and public health · 2021Article
- Determinants of completion of cancer directed treatment: an experience from a rural cancer centre, Sangrur, Punjab state, India.Ecancermedicalscience · 2021Article
- Factors Associated With Patient's Refusal of Recommended Cancer Surgery: Based on Surveillance, Epidemiology, and End Results.Frontiers in public health · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe incidence of lung cancer is increasing with longer life expectancy. Refusal of active treatment for cancer is prone to cause patients to experience more severe symptoms and shorten survival. The purpose of this study was to define the factors related to refusal or abandonment of active therapy in lung cancer.
methodsWe retrospectively reviewed the data of 617 patients from medical records from 2010 to 2014. Two groups were formed: 149 patients who refused anti-cancer treatment and allowed only palliative care were classified into the non-treatment group, while the remaining 468 who received anti-cancer treatment were classified into the treatment group.
resultsThe groups differed significantly in age, employment, relationship status, number of offspring, educational status, body mass index, presence of chest and systemic symptoms, Charlson Comorbidity Index, Eastern Cooperative Oncology Group score, and tumor node metastasis stage ( P < 0.05). In logistic regression analysis, age (odds ratio [OR] 1.10, 95% confidence interval [CI] 1.07-1.13), educational status lower than high school (OR 1.95, 95% CI 1.2-3.2), no history of surgery (OR 2.29, 95% CI 1.4-3.7), body mass index < 18.5 (OR 2.49, 95% CI 1.3-4.7), and a high Eastern Cooperative Oncology Group score of 3 or 4 (OR 5.02, 95% CI 2.3-10.8) were significant factors for refusal of cancer treatment.
conclusionIndividual factors, such as old age, low educational status, low weight, and poor performance status can influence refusal of cancer treatment in patients with lung cancer, and should be considered prior to consultation with patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.