SynthesisThe Cochrane database of systematic reviews2017
Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years.
Synthesis in The Cochrane database of systematic reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04112251 (Effect of Cocoa Flavonols Oral Supplement on Body Composition, Metabolic, Inflammatory and Oxidative Profile in Obese Subject 10 to 16 Years), which is not on this map. Cited by 258 papers, 25 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Cocoa Flavonols Oral Supplement on Body Composition, Metabolic, Inflammatory and Oxidative Profile in Obese Subject 10 to 16 Years
Who cites it
258 citing papers in PubMed, 25 syntheses or guidelines pooled it, 523 citations in OpenAlex.
- A Systematic Review and Meta-Analysis of Randomized Controlled Trials of Behavioral Interventions for the Management of Overweight and Obesity in Children That Are Delivered or Referred to by Health Providers in Primary Care.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Efficacy and safety of probiotic/synbiotic supplementation for overweight or obese children: a systematic review and meta-analysis of randomized controlled trials.Pediatric research · 2026Pooled it
- Metabolically obese normal weight phenotype in children and adolescents aged 3 to 18 years: a systematic review.BMJ paediatrics open · 2026Pooled it
- Neighborhood Environments and Changes in Obesity and in Lifestyle Behaviors Among Children Enrolled in Obesity Management Interventions: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Identifying Key Predictors of Mid-Childhood Obesity in a Population-Based Cohort Study: An Evidence Synthesis and Predictive Modeling Study.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025Pooled it
- The role of motivation in weight reduction programs for children and adolescents with overweight or obesity: a systematic review.Eating and weight disorders : EWD · 2025Pooled it
- Diet therapy for the management of obesity in children and adolescents: Overview of systematic reviews and meta-analysis of randomized controlled trials.Annals of the New York Academy of Sciences · 2025Pooled it
- Pooled it
- Interventions to prevent obesity in children aged 12 to 18 years old.The Cochrane database of systematic reviews · 2024Pooled it
- Interventions to prevent obesity in children aged 5 to 11 years old.The Cochrane database of systematic reviews · 2024Pooled it
- Efficacy of eHealth interventions to reduce depression symptoms in individuals with obesity: a systematic review of randomized controlled trials.Frontiers in psychiatry · 2024Pooled it
- The effectiveness of group-based, parent-only weight management interventions for children and the factors associated with outcomes: a systematic review.International journal of obesity (2005) · 2024Pooled it
- The effect of psychological interventions targeting overweight and obesity in school-aged children: a systematic review and meta-analysis.BMC public health · 2023Pooled it
- Surgery for the treatment of obesity in children and adolescents.The Cochrane database of systematic reviews · 2022Pooled it
- [Strategies and effects of digital interventions in overweight and obesity treatments in children and adolescents-a systematic review].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022Pooled it
- Beyond bariatric surgery and weight loss medicaments. A systematic review of the current practice in obesity rehabilitative inpatient programs in adults and pediatrics.Frontiers in nutrition · 2022Pooled it
- Guidelines for treating child and adolescent obesity: A systematic review.Frontiers in nutrition · 2022Pooled it
- Parent Involvement in Diet or Physical Activity Interventions to Treat or Prevent Childhood Obesity: An Umbrella Review.Nutrients · 2021Pooled it
- The association between adverse childhood experiences and childhood obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Pooled it
- School-based interventions for the treatment of childhood obesity: a systematic review, meta-analysis and meta-regression of cluster randomised controlled trials.Public health nutrition · 2021Pooled it
198 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 6 countries.
Funding
Abstract
backgroundChild and adolescent overweight and obesity has increased globally, and can be associated with significant short- and long-term health consequences. This is an update of a Cochrane review published first in 2003, and updated previously in 2009. However, the update has now been split into six reviews addressing different childhood obesity treatments at different ages.
objectivesTo assess the effects of diet, physical activity and behavioural interventions (behaviour-changing interventions) for the treatment of overweight or obese children aged 6 to 11 years. SEARCH
methodsWe searched CENTRAL, MEDLINE, Embase, PsycINFO, CINAHL, LILACS as well as trial registers ClinicalTrials.gov and ICTRP Search Portal. We checked references of studies and systematic reviews. We did not apply any language restrictions. The date of the last search was July 2016 for all databases. SELECTION CRITERIA: We selected randomised controlled trials (RCTs) of diet, physical activity, and behavioural interventions (behaviour-changing interventions) for treating overweight or obese children aged 6 to 11 years, with a minimum of six months' follow-up. We excluded interventions that specifically dealt with the treatment of eating disorders or type 2 diabetes, or included participants with a secondary or syndromic cause of obesity. DATA COLLECTION AND ANALYSIS: Two review authors independently screened references, extracted data, assessed risk of bias, and evaluated the quality of the evidence using the GRADE instrument. We contacted study authors for additional information. We carried out meta-analyses according to the statistical guidelines in the Cochrane Handbook for Systematic Reviews of Interventions. MAIN
resultsWe included 70 RCTs with a total of 8461 participants randomised to either the intervention or control groups. The number of participants per trial ranged from 16 to 686. Fifty-five trials compared a behaviour-changing intervention with no treatment/usual care control and 15 evaluated the effectiveness of adding an additional component to a behaviour-changing intervention. Sixty-four trials were parallel RCTs, and four were cluster RCTs. Sixty-four trials were multicomponent, two were diet only and four were physical activity only interventions. Ten trials had more than two arms. The overall quality of the evidence was low or very low and 62 trials had a high risk of bias for at least one criterion. Total duration of trials ranged from six months to three years. The median age of participants was 10 years old and the median BMI z score was 2.2.Primary analyses demonstrated that behaviour-changing interventions compared to no treatment/usual care control at longest follow-up reduced BMI, BMI z score and weight. Mean difference (MD) in BMI was -0.53 kg/m AUTHORS'
conclusionsMulti-component behaviour-changing interventions that incorporate diet, physical activity and behaviour change may be beneficial in achieving small, short-term reductions in BMI, BMI z score and weight in children aged 6 to 11 years. The evidence suggests a very low occurrence of adverse events. The quality of the evidence was low or very low. The heterogeneity observed across all outcomes was not explained by subgrouping. Further research is required of behaviour-changing interventions in lower income countries and in children from different ethnic groups; also on the impact of behaviour-changing interventions on health-related quality of life and comorbidities. The sustainability of reduction in BMI/BMI z score and weight is a key consideration and there is a need for longer-term follow-up and further research on the most appropriate forms of post-intervention maintenance in order to ensure intervention benefits are sustained over the longer term.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.