ReviewJournal of endocrinological investigation2017
Drug-induced obesity and its metabolic consequences: a review with a focus on mechanisms and possible therapeutic options.
Review in Journal of endocrinological investigation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05394779 (Evaluation of Performance and Safety of DTXO App, an Innovative Digital Therapy, in Improving Weight Loss and Weight-Loss Maintenance of Patients With Obesity by Increasing Their Adherence to Dietary, Exercise Regimens and Psycho-Behavioral Program), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Performance and Safety of DTXO App, an Innovative Digital Therapy, in Improving Weight Loss and Weight-Loss Maintenance of Patients With Obesity by Increasing Their Adherence to Dietary, Exercise Regimens and Psycho-Behavioral Program
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Very-low-calorie ketogenic diet (VLCKD) in the management of metabolic diseases: systematic review and consensus statement from the Italian Society of Endocrinology (SIE).Journal of endocrinological investigation · 2019Pooled it
- The Influence of Pre-Exercise Snacking on Glycemic Control, Physical Activity, Sleep, and Subjective Mood and Hunger During a 30-h Fast: A Randomized Crossover Study.European journal of sport science · 2025Trial
- Trial
- The Effects of Exercise on Appetite-Regulating Hormone Concentrations over a 36-h Fast in Healthy Young Adults: A Randomized Crossover Study.Nutrients · 2023Trial
- Circadian influences on glycemic control in 24-hr fasts initiated at different mealtimes.Frontiers in nutrition · 2026Article
- Role of the xenobiotic-activated pregnane X receptor in type 1 and type 2 diabetes in male mice.Biochemical pharmacology · 2026Article
- The effects of initiating a 24-hour fast with a low versus a high carbohydrate shake on glycemic control in older adults: a randomized crossover study.Nutrition & metabolism · 2025Article
- Obesogens: a unifying theory for the global rise in obesity.International journal of obesity (2005) · 2024Review
- Effects of Pharmaceutical Substances with Obesogenic Activity on Male Reproductive Health.International journal of molecular sciences · 2024Review
- A Qualitative Exploration of Postoperative Bariatric Patients' Psychosocial Support for Long-Term Weight Loss and Psychological Wellbeing.Behavioral sciences (Basel, Switzerland) · 2024Article
- Body composition and metabolic consequences of antibiotics most frequently administered to newborns in intensive care units: an experimental study in healthy newborn rats.Frontiers in medicine · 2024Article
- [Metabolic morbidity in the prison population of Catalonia, Spain].Atencion primaria · 2023Observational
- Nuclear receptor 5A2 regulation of Agrp underlies olanzapine-induced hyperphagia.Molecular psychiatry · 2023Review
- Pharmacological Treatments and Natural Biocompounds in Weight Management.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Article
- Obesogenic and leptogenic medication utilization in people with obesity: Is there a prescription for improvement?Lancet regional health. Americas · 2022Article
- Socioeconomic status and use of obesogenic and anti-obesity medications in the United States: A population-based study.Lancet regional health. Americas · 2022Article
- Obesity II: Establishing causal links between chemical exposures and obesity.Biochemical pharmacology · 2022Review
- Interactions between Food and Drugs, and Nutritional Status in Renal Patients: A Narrative Review.Nutrients · 2022Review
- Use of prescription medications associated with weight gain among US adults, 1999-2018: A nationally representative survey.Obesity (Silver Spring, Md.) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Weight gain is a common side effect of many widely used drugs. Weight gain of a few kilograms to an increase of 10% or more of initial body weight has been described. Not only the weight gain as such puts a burden on the health risks of the involved patients, the accompanying increase in the incidence of the metabolic syndrome, type 2 diabetes mellitus, and cardiovascular risk factors urges the caregiver to identify and to closely monitor the patients at risk. In this review, the different classes of drugs with significant weight gaining properties and the metabolic consequences are described. Specific attention is given to pathogenetic mechanisms underlying the metabolic effects and to potential therapeutic measures to prevent them.
Indexed as
Identifiers
28660606What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.