Evidence map›Paper›PMID 28665270›Full record

ArticleeLife2017

Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division.

Jennifer J Banerjee, Birgit L Aerne, Maxine V Holder, Simon Hauri, Matthias Gstaiger, Nicolas Tapon

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. PARD3 gene variation as candidate cause of nonsyndromic cleft palate only.Journal of cellular and molecular medicine · 2022
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer J BanerjeeApoptosis and Proliferation Control Laboratory, The Francis Crick Institute, London, United Kingdom.
Birgit L AerneApoptosis and Proliferation Control Laboratory, The Francis Crick Institute, London, United Kingdom.
Maxine V HolderApoptosis and Proliferation Control Laboratory, The Francis Crick Institute, London, United Kingdom.
Simon HauriDepartment of Biology, Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland.
Matthias GstaigerDepartment of Biology, Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland.
Nicolas TaponApoptosis and Proliferation Control Laboratory, The Francis Crick Institute, London, United Kingdom.ORCID 0000-0001-5267-6510

Funding

Cancer Research UK 17064Cancer Research UK FC001175Medical Research Council FC001175Wellcome Trust 107885/Z/15/ZWellcome Trust FC001175
6 · The paper itself

Abstract

Polarity is a shared feature of most cells. In epithelia, apical-basal polarity often coexists, and sometimes intersects with planar cell polarity (PCP), which orients cells in the epithelial plane. From a limited set of core building blocks (e.g. the Par complexes for apical-basal polarity and the Frizzled/Dishevelled complex for PCP), a diverse array of polarized cells and tissues are generated. This suggests the existence of little-studied tissue-specific factors that rewire the core polarity modules to the appropriate conformation. In

Indexed as

Asymmetric Cell DivisionCell PolarityGene Expression Regulation, DevelopmentalAnimalsDrosophilaDrosophila ProteinsGene Expression ProfilingVesicular Transport ProteinsDrosophila Proteinsmeru protein, DrosophilaVesicular Transport Proteinsapical-basal polarityasymmetric cell divisionBazooka/Par3developmental biologyD. melanogasterplanar cell polarityRASSF9/RASSF10sensory organ precursorstem cells

Identifiers

PMID28665270
PMCPMC5493435

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.