Evidence map›Paper›PMID 28686181›Full record

ReviewMolecules (Basel, Switzerland)2017

How Can Synergism of Traditional Medicines Benefit from Network Pharmacology?

Haidan Yuan, Qianqian Ma, Heying Cui, Guancheng Liu, Xiaoyan Zhao, Wei Li, Guangchun Piao

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04627519 (A Multicenter, Randomized, Open-label, Controlled Trial to Assess Effectiveness and Safety of Rhea Health Tone® as add-on Therapy for COVID-19 in Hospitalized Adults in Indonesia), which is not on this map. Cited by 217 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
217citing papers in PubMed, 3 pooled it
19.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04627519 naunknown statusnot on this mapstarted 2020, after this paper: background citation

A Multicenter, Randomized, Open-label, Controlled Trial to Assess Effectiveness and Safety of Rhea Health Tone® as add-on Therapy for COVID-19 in Hospitalized Adults in Indonesia

TypeinterventionalSponsorUniversitas PadjadjaranRan2020 to 2021Enrolled85ConditionsCovid19ArmsRhea Health Tone®
3 · Its place in the literature

Who cites it

217 citing papers in PubMed, 3 syntheses or guidelines pooled it, 443 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A HeterogeneousInternational journal of molecular sciences · 2026
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  18. Multifunctional Dermatological Effects of Whole-PlantCurrent issues in molecular biology · 2025
    Article
  19. Article
  20. Article

157 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Haidan YuanCollege of Pharmacy, Yanbian University; 977 Gongyuan Street, Yanji 133002, China. hdyuan@ybu.edu.cn.
Qianqian MaCollege of Pharmacy, Yanbian University; 977 Gongyuan Street, Yanji 133002, China. qianqian3918@163.com.
Heying CuiCollege of Traditional Chinese Medicine, Yanbian University; Yanji 133002, China. kimmy@ybu.edu.cn.
Guancheng LiuCollege of Pharmacy, Yanbian University; 977 Gongyuan Street, Yanji 133002, China. 15504336519@163.com.
Xiaoyan ZhaoCollege of Pharmacy, Yanbian University; 977 Gongyuan Street, Yanji 133002, China. 2015010622@ybu.edu.cn.
Wei LiCollege of Pharmacy, Yanbian University; 977 Gongyuan Street, Yanji 133002, China. 2015010629@ybu.edu.cn.
Guangchun PiaoCollege of Pharmacy, Yanbian University; 977 Gongyuan Street, Yanji 133002, China. hdyuan@ybu.edu.cn.
Yanbian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug SynergismDrug DiscoveryDrug InteractionsDrugs, Chinese HerbalHumansMedicine, TraditionalDrugs, Chinese Herbal.drug discoverynetwork pharmacologysynergistic effectstraditional medicines

Identifiers

PMID28686181
PMCPMC6152294
OpenAlexW2728621008

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.