Evidence map›Paper›PMID 28690587›Full record

ArticleFrontiers in neurology2017

Brain Connectivity Patterns Dissociate Action of Specific Acupressure Treatments in Fatigued Breast Cancer Survivors.

Richard E Harris, Eric Ichesco, Chelsea Cummiford, Johnson P Hampson, Thomas L Chenevert, Neil Basu, Suzanna M Zick

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Determining the feasibility of self-administered relaxing acupressure for fatigue among adolescent and young adult cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  4. Trial
  5. Article
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  8. Virtual acupressure for symptom management in cancer populations during COVID-19: a retrospective analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  9. Article
  10. Tailored Psychological Interventions to Manage Body Image: An Opinion Study on Breast Cancer Survivors.International journal of environmental research and public health · 2023
    Article
  11. Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Richard E HarrisDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, United States.
Eric IchescoDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, United States.
Chelsea CummifordDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, United States.
Johnson P HampsonDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, United States.
Thomas L ChenevertDepartment of Radiology, University of Michigan, Ann Arbor, MI, United States.
Neil BasuDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, United States.
Suzanna M ZickDepartment of Family Medicine, University of Michigan, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · USMichigan United · USUniversity of Aberdeen · GB

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Acupressure for Persistent Cancer Related FatigueR01CA151445 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HARRIS, RICHARD E, ZICK, SUZANNA M. · 2010 to 2014
$2.3M
NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240NCI NIH HHS R01 CA151445
6 · The paper itself

Abstract

Persistent fatigue is a pernicious symptom in many cancer survivors. Existing treatments are limited or ineffective and often lack any underlying biologic rationale. Acupressure is emerging as a promising new intervention for persistent cancer-related fatigue; however, the underlying mechanisms of action are unknown. Our previous investigations suggested that fatigued breast cancer survivors have alterations in brain neurochemistry within the posterior insula and disturbed functional connectivity to the default mode network (DMN), as compared to non-fatigued breast cancer survivors. Here, we investigated if insula and DMN connectivity were modulated by self-administered acupressure by randomizing breast cancer survivors (

Indexed as

acupressurecancer survivorsconnectivityfatiguespectroscopy

Identifiers

PMID28690587
PMCPMC5481304
OpenAlexW2700184369

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.