Evidence map›Paper›PMID 28694806›Full record

ArticleFrontiers in immunology2017

A Bivalent Anthrax-Plague Vaccine That Can Protect against Two Tier-1 Bioterror Pathogens,

Pan Tao, Marthandan Mahalingam, Jingen Zhu, Mahtab Moayeri, Michelle L Kirtley, Eric C Fitts, Jourdan A Andersson, William S Lawrence, Stephen H Leppla, Ashok K Chopra and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Biodefence research two decades on: worth the investment?The Lancet. Infectious diseases · 2021
    Review
  3. Article
  4. Review
  5. Deliberate release: Plague - A review.Journal of biosafety and biosecurity · 2020
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Pan TaoDepartment of Biology, The Catholic University of America, Washington, DC, United States.
Marthandan MahalingamDepartment of Biology, The Catholic University of America, Washington, DC, United States.
Jingen ZhuDepartment of Biology, The Catholic University of America, Washington, DC, United States.
Mahtab MoayeriMicrobial Pathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Michelle L KirtleyDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Eric C FittsDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Jourdan A AnderssonDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
William S LawrenceDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Stephen H LepplaMicrobial Pathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Ashok K ChopraDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, United States.
Venigalla B RaoDepartment of Biology, The Catholic University of America, Washington, DC, United States.
The University of Texas Medical Branch at Galveston · USCatholic University of America · USUniversity of America · USNational Institute of Allergy and Infectious Diseases · USNational Institutes of Health · US

Funding

Vaccines and Therapeutics for AnthraxZIAAI000929 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LEPPLA, STEPHEN · 2009 to 2025
$15.9M
Identification of New Antigens for a Plague VaccineR01AI064389 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI CHOPRA, ASHOK K · 2005 to 2015
$3.8M
Single Dose, Multivalent, Anthrax Plague Vaccines using Bacteriophage T4 NanopartR01AI111538 · NIAID · CATHOLIC UNIVERSITY OF AMERICA · PI RAO, VENIGALLA B. · 2014 to 2018
$3.6M
A Multicomponent Anthrax Vaccine using Phage T4 DisplayU01AI056443 · NIAID · CATHOLIC UNIVERSITY OF AMERICA · PI RAO, VENIGALLA B. · 2003 to 2007
$3.3M
Biodefense Training ProgramT32AI060549 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ASHOK K CHOPRA, Janice J Endsley · 2004 to 2026
$3.0M
Multivalent Plague, Anthrax Vaccines Using Bacteriophage T4 DisplayU01AI082086 · NIAID · CATHOLIC UNIVERSITY OF AMERICA · PI RAO, VENIGALLA B. · 2009 to 2013
$2.2M
Potent Phage T4 Derived V2 Immunogens as HIV VaccinesR01AI102725 · NIAID · CATHOLIC UNIVERSITY OF AMERICA · PI RAO, VENIGALLA B. · 2012 to 2015
$1.7M
NIAID NIH HHS R01 AI064389NIAID NIH HHS R01 AI102725NIAID NIH HHS R01 AI111538NIAID NIH HHS T32 AI060549NIAID NIH HHS U01 AI056443NIAID NIH HHS U01 AI082086
6 · The paper itself

Abstract

Bioterrorism remains as one of the biggest challenges to global security and public health. Since the deadly anthrax attacks of 2001 in the United States,

Indexed as

anthrax vaccinesbiodefense vaccinesbivalent vaccinescapsular antigen f1low calcium response V antigen LcrVplague vaccineprotective antigen

Identifiers

PMID28694806
PMCPMC5483451
OpenAlexW4237215992

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.