Evidence map›Paper›PMID 28696214›Full record

ArticleMolecular pharmacology2017

Epigenetic Regulation by Agonist-Specific Aryl Hydrocarbon Receptor Recruitment of Metastasis-Associated Protein 2 Selectively Induces Stanniocalcin 2 Expression.

Aditya D Joshi, Ekram Hossain, Cornelis J Elferink

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Stanniocalcin 2 (STC2): a universal tumour biomarker and a potential therapeutical target.Journal of experimental & clinical cancer research : CR · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Epigenetic Regulations of AhR in the Aspect of Immunomodulation.International journal of molecular sciences · 2020
    Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Aditya D JoshiDepartment of Pharmacology and Toxicology (A.D.J., C.J.E.) and Sealy Center for Environmental Health and Medicine (E.H., C.J.E.), University of Texas Medical Branch, Galveston, Texas adjoshi@utmb.edu.
Ekram HossainDepartment of Pharmacology and Toxicology (A.D.J., C.J.E.) and Sealy Center for Environmental Health and Medicine (E.H., C.J.E.), University of Texas Medical Branch, Galveston, Texas.
Cornelis J ElferinkDepartment of Pharmacology and Toxicology (A.D.J., C.J.E.) and Sealy Center for Environmental Health and Medicine (E.H., C.J.E.), University of Texas Medical Branch, Galveston, Texas.
The University of Texas Medical Branch at Galveston · USCenter for Environmental Health · US

Funding

Synthetic Organic Chemistry CoreP30ES006676 · NIEHS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ELFERINK, CORNELIS JOHAN · 1995 to 2017
$21.7M
Aryl Hydrocarbon Receptor-Mediated Epigenetic ProcessesR01ES026874 · NIEHS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI ELFERINK, CORNELIS JOHAN · 2016 to 2020
$2.2M
A Novel Paradigm for Aryl Hydrocarbon Receptor SignalingR21ES024607 · NIEHS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI ELFERINK, CORNELIS JOHAN · 2015 to 2016
$426k
Characterization of cinnabarinic acid mediated cytoprotection upon liver injuryK01DK102514 · NIDDK · UNIVERSITY OF TEXAS MED BR GALVESTON · PI JOSHI, ADITYA D · 2015 to 2017
$279k
NIDDK NIH HHS K01 DK102514NIEHS NIH HHS P30 ES006676NIEHS NIH HHS R01 ES026874NIEHS NIH HHS R21 ES024607
6 · The paper itself

Abstract

The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates a plethora of target genes. Historically, the AhR has been studied as a regulator of xenobiotic metabolizing enzyme genes, notably cytochrome P4501A1 encoded by CYP1A1, in response to the exogenous prototypical ligand 2,3,7,8-tetrachlorodibenzo-

Indexed as

Epigenesis, GeneticAnimalsCytoprotectionFemaleGlycoproteinsHistonesIntercellular Signaling Peptides and ProteinsIntracellular Signaling Peptides and ProteinsMiceMice, Inbred BALB COxazinesPolychlorinated DibenzodioxinsPromoter Regions, GeneticReceptors, Aryl HydrocarbonRepressor ProteinsResponse Elementscinnabarinic acidGlycoproteinsHistonesIntercellular Signaling Peptides and ProteinsIntracellular Signaling Peptides and ProteinsMta2 protein, mouseOxazinesPolychlorinated DibenzodioxinsReceptors, Aryl HydrocarbonRepressor ProteinsStc2 protein, mouseTrans-Activators

Identifiers

PMID28696214
PMCPMC5553190
OpenAlexW2735842847

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.