Evidence map›Paper›PMID 28697329›Full record

ArticleDevelopmental cell2017

Lipid Droplets Guard Mitochondria during Autophagy.

Till Klecker, Ralf J Braun, Benedikt Westermann

Abstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. An Overview: The Diversified Role of Mitochondria in Cancer Metabolism.International journal of biological sciences · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Lipid Droplets and the Management of Cellular Stress.The Yale journal of biology and medicine · 2019
    Review
  14. Article
  15. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Till KleckerZellbiologie, Universität Bayreuth, 95440 Bayreuth, Germany. Electronic address: till.klecker@uni-bayreuth.de.
Ralf J BraunZellbiologie, Universität Bayreuth, 95440 Bayreuth, Germany.
Benedikt WestermannZellbiologie, Universität Bayreuth, 95440 Bayreuth, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Developmental Cell, Nguyen et al. (2017) show that lipid droplets serve a dual purpose during starvation. First, they act as an energy source by supplying fatty acids for mitochondrial β oxidation. Second, they sequester toxic lipids that arise during autophagic degradation of membranous organelles, thereby protecting mitochondria.

Indexed as

AutophagyLipid DropletsFatty AcidsLipidsMitochondriaFatty AcidsLipids

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.