Evidence map›Paper›PMID 28703749›Full record

ReviewSensors (Basel, Switzerland)2017

The Application of Whole Cell-Based Biosensors for Use in Environmental Analysis and in Medical Diagnostics.

Qingyuan Gui, Tom Lawson, Suyan Shan, Lu Yan, Yong Liu

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed.

  1. Article
  2. Review
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  6. Enhancing Antigen Recognition of Living Cells by Site-Specific VHH Antibody Conjugation.Chembiochem : a European journal of chemical biology · 2025
    Article
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  8. Review
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28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qingyuan GuiLaboratory of Nanoscale Biosensing and Bioimaging, Instiute of Advanced Materials for Nano-Bio Applications, School of Ophthalmology and Optometry, Wenzhou Medical University, 270 Xueyuanxi Road, Wenzhou 325027, China. guiqyu@126.com.
Tom LawsonARC Center of Excellence for Nanoscale BioPhotonics, Macquarie University, Sydney, NSW 2109, Australia. tomxlawson@gmail.com.
Suyan ShanLaboratory of Nanoscale Biosensing and Bioimaging, Instiute of Advanced Materials for Nano-Bio Applications, School of Ophthalmology and Optometry, Wenzhou Medical University, 270 Xueyuanxi Road, Wenzhou 325027, China. shan_suyan@163.com.
Lu YanLaboratory of Nanoscale Biosensing and Bioimaging, Instiute of Advanced Materials for Nano-Bio Applications, School of Ophthalmology and Optometry, Wenzhou Medical University, 270 Xueyuanxi Road, Wenzhou 325027, China. yanlu2017@wmu.edu.cn.
Yong LiuLaboratory of Nanoscale Biosensing and Bioimaging, Instiute of Advanced Materials for Nano-Bio Applications, School of Ophthalmology and Optometry, Wenzhou Medical University, 270 Xueyuanxi Road, Wenzhou 325027, China. yongliu1980@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various whole cell-based biosensors have been reported in the literature for the last 20 years and these reports have shown great potential for their use in the areas of pollution detection in environmental and in biomedical diagnostics. Unlike other reviews of this growing field, this mini-review argues that: (1) the selection of reporter genes and their regulatory proteins are directly linked to the performance of celllular biosensors; (2) broad enhancements in microelectronics and information technologies have also led to improvements in the performance of these sensors; (3) their future potential is most apparent in their use in the areas of medical diagnostics and in environmental monitoring; and (4) currently the most promising work is focused on the better integration of cellular sensors with nano and micro scaled integrated chips. With better integration it may become practical to see these cells used as (5) real-time portable devices for diagnostics at the bedside and for remote environmental toxin detection and this in situ application will make the technology commonplace and thus as unremarkable as other ubiquitous technologies.

Indexed as

Biosensing TechniquesEnvironmental MonitoringGenes, ReporterHumansbacteriabioluminescencedetectiondiagnosisenvironmental analysisliving cellsreporterssensorswhole cell biosensors

Identifiers

PMID28703749
PMCPMC5539819

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.