Evidence map›Paper›PMID 28705804›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2017

Loss of nitric oxide-mediated inhibition of purine neurotransmitter release in the colon in the absence of interstitial cells of Cajal.

Leonie Durnin, Andrea Lees, Sheerien Manzoor, Kent C Sasse, Kenton M Sanders, Violeta N Mutafova-Yambolieva

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Excitatory cholinergic responses in mouse colon intramuscular interstitial cells of Cajal are due to enhanced CaFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  7. CaThe Journal of physiology · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Inhibitory Neural Regulation of the CaFrontiers in physiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Leonie DurninDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada; and.
Andrea LeesDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada; and.
Sheerien ManzoorDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada; and.
Kent C SasseSasse Surgical Associates, Reno, Nevada.
Kenton M SandersDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada; and.
Violeta N Mutafova-YambolievaDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada; and vmutafova@med.unr.edu.
University of Nevada, Reno · US

Funding

Tissue, Cell and Tissue Culture CoreP01DK041315 · NIDDK · UNIVERSITY OF NEVADA RENO · PI KEEF, KATHLEEN D · 1989 to 2018
$26.3M
NIDDK NIH HHS P01 DK041315
6 · The paper itself

Abstract

Regulation of colonic motility depends on the integrity of enteric inhibitory neurotransmission mediated by nitric oxide (NO), purine neurotransmitters, and neuropeptides. Intramuscular interstitial cells of Cajal (ICC-IM) and platelet-derived growth factor receptor-α-positive (PDGFRα

Indexed as

ColonGastrointestinal MotilityInterstitial Cells of CajalPurinesAnimalsHaplorhiniHumansMembrane PotentialsMiceNeurotransmitter AgentsNitric OxideReceptor, Platelet-Derived Growth Factor alphaSoluble Guanylyl CyclaseSynaptic TransmissionNeurotransmitter AgentsNitric OxidePurinesReceptor, Platelet-Derived Growth Factor alphaSoluble Guanylyl Cyclasecoloninterstitial cell of Cajalnitric oxidepurinergicW/Wv mice

Identifiers

PMID28705804
PMCPMC5792210
OpenAlexW2735863434

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.