ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2018
Pancreatic allograft thrombosis: Suggestion for a CT grading system and management algorithm.
Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Risk Factors for Early Pancreatic Allograft Thrombosis Following Simultaneous Pancreas-Kidney Transplantation: A Systematic Review.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisPooled it
- Clinical outcomes of simultaneous pancreas-kidney transplantation: experience of a single center.Fukushima journal of medical science · 2025Article
- Dueling with the dual artery blood supply in pancreas transplantation: why replace the Y?Gland surgery · 2024Article
- Comprehensive review of imaging in pancreas transplantation: a primer for radiologists.Abdominal radiology (New York) · 2024Review
- Local Postoperative Graft Inflammation in Pancreas Transplant Patients With Early Graft Thrombosis.Transplantation direct · 2024Article
- Surgical complications after pancreatic transplantation: A computed tomography imaging pictorial review.World journal of gastroenterology · 2023Review
- Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation.Frontiers in immunology · 2023Observational
- Pancreatic Allograft Thrombosis: Implementation of the CPAT-Grading System in a Retrospective Series of Simultaneous Pancreas-Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Modification of Venous Outflow to Avoid Thrombotic Graft Failure in Pancreas Transplantation.Annals of transplantation · 2022Article
- Improved surgical outcomes following simultaneous pancreas-kidney transplantation in the contemporary era.Clinical transplantation · 2022Article
- Salvage of Graft Pancreas in a Simultaneous Pancreas-kidney Transplant Recipient With Splenic Artery Thrombosis, Infected Walled-off Necrosis, and Stenting of Y Arterial Graft Stenosis.Transplantation direct · 2022Article
- Article
- Effective Technique for Pancreas Transplantation by Iliac Vascular Transposition, Without Heparin-Based Anticoagulation Therapy.World journal of surgery · 2022Article
- Outcomes for circulatory death and brainstem death pancreas transplantation with or without use of normothermic regional perfusion.The British journal of surgery · 2021Article
- Accelerating cryoprotectant diffusion kinetics improves cryopreservation of pancreatic islets.Scientific reports · 2021Article
- Working towards an ERAS Protocol for Pancreatic Transplantation: A Narrative Review.Journal of clinical medicine · 2021Review
- Immediate post-operative complications (I): Post-operative bleeding; vascular origin: Thrombosis pancreatitis.World journal of transplantation · 2020Review
- Anticoagulation in simultaneous pancreas kidney transplantation - On what basis?World journal of transplantation · 2020Article
- Retrospective study on detection, treatment, and clinical outcome of graft thrombosis following pancreas transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2019Article
- Fence Angioplasty Prevents Narrowing of Venous Anastomosis in Solitary Pancreas Transplant.Annals of transplantation · 2018Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pancreatic allograft thrombosis (PAT) remains the leading cause of nonimmunologic graft failure. Here, we propose a new computed tomography (CT) grading system of PAT to identify risk factors for allograft loss and outline a management algorithm by retrospective review of consecutive pancreatic transplantations between 2009 and 2014. Triple-phase CT scans were graded independently by 2 radiologists as grade 0, no thrombosis; grade 1, peripheral thrombosis; grade 2, intermediate non-occlusive thrombosis; and grade 3, central occlusive thrombosis. Twenty-four (23.3%) of 103 recipients were diagnosed with PAT (including grade 1). Three (2.9%) grafts were lost due to portal vein thrombosis. On multivariate analysis, pancreas after simultaneous pancreas-kidney transplantation/solitary pancreatic transplantation, acute rejection, and CT findings of peripancreatic edema and/or inflammatory change were significant risk factors for PAT. Retrospective review of CT scans revealed more grade 1 and 2 thromboses than were initially reported. There was no significant difference in graft or patient survival, postoperative stay, or morbidity of recipients with grade 1 or 2 thrombosis who were or were not anticoagulated. Our data suggest that therapeutic anticoagulation is not necessary for grade 1 and 2 arterial and grade 1 venous thrombosis. The proposed grading system can assist clinicians in decision-making and provide standardized reporting for future studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.