SynthesisMedical science monitor : international medical journal of experimental and clinical research2017
Association Between Diabetes Mellitus and Outcomes of Patients with Sepsis: A Meta-Analysis.
Synthesis in Medical science monitor : international medical journal of experimental and clinical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 54 citations in OpenAlex.
- Timing-dependent renal protection of dapagliflozin in endotoxemic diabetic mice by real-time GFR and biomarkers.Intensive care medicine experimental · 2026Article
- Association Between Type 2 Diabetes Mellitus and Sepsis Outcomes: A Systematic Review and Meta-Analysis.Cureus · 2026Review
- The interplay between type 2 diabetes mellitus and sepsis: a scoping review.International journal of medical sciences · 2026Article
- The effect of insulin on 28-day mortality in non-diabetic sepsis patients: a retrospective study.Frontiers in cellular and infection microbiology · 2026Article
- Association of triglyceride glucose index with sepsis risk after major abdominal surgery: A retrospective cohort study.Pakistan journal of medical sciences · 2025Article
- XueBiJing injection reduced mortality in sepsis patients with diabetes.Frontiers in pharmacology · 2025Article
- Article
- Preexisting Diabetes Mellitus and All-Cause Mortality in Adult Patients With Sepsis: A Population-Based Cohort Study.Critical care explorations · 2024Article
- Poor treatment outcome and associated factors of hyperglycemic emergencies among diabetic patients in Ethiopia: A systematic review and meta-analysis.Metabolism open · 2024Article
- Prevalent diabetes and long-term cardiovascular outcomes in adult sepsis survivors: a population-based cohort study.Critical care (London, England) · 2023Article
- National emergency department trends for endogenous endophthalmitis: an increasing public health challenge.Eye (London, England) · 2023Article
- Review
- Impact of diabetes mellitus on outcomes of patients with sepsis: an updated systematic review and meta-analysis.Diabetology & metabolic syndrome · 2022Review
- Association between glucose-to-lymphocyte ratio and in-hospital mortality in intensive care patients with sepsis: A retrospective observational study based on Medical Information Mart for Intensive Care IV.Frontiers in medicine · 2022Article
- Anti-diabetics and antimicrobials: Harmony of mutual interplay.World journal of diabetes · 2021Review
- Type 2 diabetes mellitus and sepsis: state of the art, certainties and missing evidence.Acta diabetologica · 2021Review
- Sepsis and Cerebral Dysfunction: BBB Damage, Neuroinflammation, Oxidative Stress, Apoptosis and Autophagy as Key Mediators and the Potential Therapeutic Approaches.Neurotoxicity research · 2021Review
- History of diabetes may delay antibiotic administration in patients with severe sepsis presenting to emergency departments.Medicine · 2020Article
- Association between Statin Use and Sepsis Risk in Patients with Dementia: A Retrospective Cohort Study.International journal of environmental research and public health · 2019Article
- The diabetes pandemic and associated infections: suggestions for clinical microbiology.Reviews in medical microbiology : a journal of the Pathological Society of Great Britain and Ireland · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Diabetes mellitus (DM) is a critical medical problem that can make people more likely to develop infectious complications, even sepsis. However, the influence of DM on the outcomes of septic patients is still controversial. Thus, we conducted the present meta-analysis to investigate whether DM worsens outcomes of septic patients. MATERIAL AND METHODS We searched studies from PubMed, Embase, and Cochrane Library databases from 1966 to July 1, 2016. The primary outcome we chose was 28-day or 30-day mortality or in-hospital mortality. RESULTS Our meta-analysis of 10 enrolled studies performed between 2000 and 2016 shows that the mortality rate of septic patients with DM was slightly lower than that of non-diabetic patients (risk ratio [RR]=0.97, 95% confidence interval [CI]: 0.96 to 0.98, P<0.00001). On the other hand, septic patients with DM had a shorter hospital stay (weighted mean difference (WMD)=-2.27, 95% CI: -4.11 to -0.44, P=0.01), a higher incidence rate of AKI (RR=1.56, 95% CI: 1.25 to 1.95, P<0.001), and a similar incidence of respiratory dysfunction (RR=0.86, 95% CI: 0.71 to 1.04, P=0.11) compared with those without DM. CONCLUSIONS The results from the meta-analysis suggest that DM does not impair the outcome of patients with sepsis, and the incidence of acute kidney injury increases dramatically in septic patients with DM. Due to the limitations of the analysis, more well-designed trials are still necessary.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.