Evidence map›Paper›PMID 28732200›Full record

ArticleCell chemical biology2017

Systematic Metrics Depicting Cell Death Kinetics.

Ying Li, Junying Yuan

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ying LiInterdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Rd, Pudong, Shanghai 201210, China.
Junying YuanInterdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Rd, Pudong, Shanghai 201210, China; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA. Electronic address: jyuan@hms.harvard.edu.

Funding

Investigating the neuroinflammatory role of RIP1 kinaseR01AG047231 · NIA · HARVARD MEDICAL SCHOOL · PI YUAN, JUNYING · 2014 to 2018
$2.2M
Investigating the mechanism of TNFalpha mediated cell death in oligodendrocytesR01NS082257 · NINDS · HARVARD MEDICAL SCHOOL · PI YUAN, JUNYING · 2013 to 2017
$1.9M
NIA NIH HHS R01 AG047231NINDS NIH HHS R01 NS082257
6 · The paper itself

Abstract

In a recent issue of Cell Systems, Forcina et al. (2017) developed a scalable time-lapse analysis of cell death kinetics (STACK) method and combined it with a "lag exponential death" model to quantitatively characterize the onset and rate of cell death. STACK provides a useful quantitative tool to determine how cell death kinetics may be modulated pharmacologically in cell culture systems.

Indexed as

Cell DeathModels, BiologicalCell Culture TechniquesCell CycleCell DivisionCell SurvivalKineticsPhysicsTemperature

Identifiers

PMID28732200

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.