Evidence map›Paper›PMID 28735240›Full record

ArticleRedox biology2017

Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H

Song Liu, Danqing Xin, Lingxiao Wang, Tiantian Zhang, Xuemei Bai, Tong Li, Yunkai Xie, Hao Xue, Shishi Bo, Dexiang Liu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Age-dependent effects of HFrontiers in psychiatry · 2025
    Article
  5. The role of hydrogen sulfide regulation of ferroptosis in different diseases.Apoptosis : an international journal on programmed cell death · 2024
    Review
  6. The Role of Cystathionine-β-Synthase, HJournal of molecular neuroscience : MN · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Song LiuDepartment of Physiology, Shandong University School of Basic Medical Sciences, 44#, Wenhua Xi Road, Jinan, Shandong 250012, PR China.
Danqing XinDepartment of Physiology, Shandong University School of Basic Medical Sciences, 44#, Wenhua Xi Road, Jinan, Shandong 250012, PR China.
Lingxiao WangDepartment of Physiology, Shandong University School of Basic Medical Sciences, 44#, Wenhua Xi Road, Jinan, Shandong 250012, PR China.
Tiantian ZhangDepartment of Physiology, Shandong University School of Basic Medical Sciences, 44#, Wenhua Xi Road, Jinan, Shandong 250012, PR China.
Xuemei BaiDepartment of Physiology, Shandong University School of Basic Medical Sciences, 44#, Wenhua Xi Road, Jinan, Shandong 250012, PR China.
Tong LiDepartment of Physiology, Shandong University School of Basic Medical Sciences, 44#, Wenhua Xi Road, Jinan, Shandong 250012, PR China.
Yunkai XieDepartment of Medical Psychology, Shandong University School of Basic Medical Sciences, 44#, Wenhua Xi Road, Jinan, Shandong 250012, PR China.
Hao XueDepartment of Neurosurgery, Qilu Hospital of Shandong University and Brain Science Research Institute, Shandong University, 107#, Wenhua Xi Road, Jinan, Shandong Province 250012, PR China.
Shishi BoDepartment of Physiology, Shandong University School of Basic Medical Sciences, 44#, Wenhua Xi Road, Jinan, Shandong 250012, PR China.
Dexiang LiuDepartment of Medical Psychology, Shandong University School of Basic Medical Sciences, 44#, Wenhua Xi Road, Jinan, Shandong 250012, PR China.
Zhen WangDepartment of Physiology, Shandong University School of Basic Medical Sciences, 44#, Wenhua Xi Road, Jinan, Shandong 250012, PR China. Electronic address: wangzhen@sdu.edu.cn.
Shandong University · CNQilu Hospital of Shandong University · CNShandong First Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal hypoxic-ischemic (HI) injury is a major cause of neonatal death and neurological dysfunction. H

Indexed as

Endoplasmic Reticulum StressOxidative StressAnimalsApoptosisCystathionine beta-SynthaseCysteineHeme Oxygenase-1Hypoxia-Ischemia, BrainMiceMice, Inbred C57BLMitogen-Activated Protein Kinase 3Neuroprotective AgentsNF-E2-Related Factor 2Proto-Oncogene Proteins c-aktSulfitesCystathionine beta-SynthaseCysteineHeme Oxygenase-1hydrogen sulfiteMitogen-Activated Protein Kinase 3Neuroprotective AgentsNF-E2-Related Factor 2Proto-Oncogene Proteins c-aktSulfitesEndoplasmic reticulum stressH(2)SHypoxia-ischemiaL-CysteineOxidative stress

Identifiers

PMID28735240
PMCPMC5524226
OpenAlexW2736212039

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.