ReviewInternational journal of molecular sciences2017
Application of Extrusion-Based Hydrogel Bioprinting for Cartilage Tissue Engineering.
Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed.
- 3D bioprinting technologies and biomaterial-based scaffolds for wound healing: Insights into decellularized tissue-derived bioinks.Regenerative therapy · 2026Review
- Recent Trends in the Development and Clinical Translation of Polymer-based Targeted Therapeutic Nanoparticle.AAPS PharmSciTech · 2026Review
- Photo Crosslinkable Hybrid Hydrogels for High Fidelity Direct Write 3D Printing: Rheology, Curing Kinetics, and Bio-Scaffold Fabrication.Journal of functional biomaterials · 2026Article
- 3D-bioprinting for joint regeneration.Frontiers in bioengineering and biotechnology · 2026Review
- High-Resolution Heterogeneous Hydrogel Printing Using a Home Projector.Small methods · 2025Article
- Review
- Development of 3D-printed Ti-MXene incorporated chitosan/HAP nano-composite soft-bone scaffold and its mechanical, anti-biofilm and cell-viability studies.Scientific reports · 2025Article
- Gynecologic postoperative anti-adhesion barriers: From biomaterials to barrier development.Biomaterials and biosystems · 2025Review
- Heterogeneous and Composite Bioinks for 3D-Bioprinting of Complex Tissue.Biomedical materials & devices (New York, N.Y.) · 2025Review
- Research advance of 3D printing for articular cartilage regeneration.Regenerative medicine · 2025Review
- Gel-Based Suspension Medium Used in 3D Bioprinting for Constructing Tissue/Organ Analogs.Gels (Basel, Switzerland) · 2024Review
- Recent Advances in the Application of 3D-Printing Bioinks Based on Decellularized Extracellular Matrix in Tissue Engineering.ACS omega · 2024Review
- Three Dimensional Bioprinting for Hepatic Tissue Engineering: From In Vitro Models to Clinical Applications.Tissue engineering and regenerative medicine · 2024Review
- 3D printing and bioprinting in the battle against diabetes and its chronic complications.Frontiers in bioengineering and biotechnology · 2024Review
- Development and Prospective Applications of 3D Membranes as a Sensor for Monitoring and Inducing Tissue Regeneration.Membranes · 2023Review
- Optimizing Bioink Composition for Human Chondrocyte Expression of Lubricin.Bioengineering (Basel, Switzerland) · 2023Article
- Reinforcement of Hydrogels with a 3D-Printed Polycaprolactone (PCL) Structure Enhances Cell Numbers and Cartilage ECM Production under Compression.Journal of functional biomaterials · 2023Article
- Applied Compressive Strain Governs Hyaline-like Cartilage versus Fibrocartilage-like ECM Produced within Hydrogel Constructs.International journal of molecular sciences · 2023Article
- A Novel Approach for Multiple Material Extrusion in Arthroscopic Knee Surgery.Annals of biomedical engineering · 2023Article
- Optimization of Freeform Reversible Embedding of Suspended Hydrogel Microspheres for Substantially Improved Three-Dimensional Bioprinting Capabilities.Tissue engineering. Part C, Methods · 2023Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extrusion-based bioprinting (EBB) is a rapidly developing technique that has made substantial progress in the fabrication of constructs for cartilage tissue engineering (CTE) over the past decade. With this technique, cell-laden hydrogels or bio-inks have been extruded onto printing stages, layer-by-layer, to form three-dimensional (3D) constructs with varying sizes, shapes, and resolutions. This paper reviews the cell sources and hydrogels that can be used for bio-ink formulations in CTE application. Additionally, this paper discusses the important properties of bio-inks to be applied in the EBB technique, including biocompatibility, printability, as well as mechanical properties. The printability of a bio-ink is associated with the formation of first layer, ink rheological properties, and crosslinking mechanisms. Further, this paper discusses two bioprinting approaches to build up cartilage constructs, i.e., self-supporting hydrogel bioprinting and hybrid bioprinting, along with their applications in fabricating chondral, osteochondral, and zonally organized cartilage regenerative constructs. Lastly, current limitations and future opportunities of EBB in printing cartilage regenerative constructs are reviewed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.