ArticleScientific reports2017
Associations of plasma homocysteine levels with peripheral systolic blood pressure and noninvasive central systolic blood pressure in a community-based Chinese population.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Associations between remnant lipoprotein cholesterol and central systolic blood pressure in a Chinese community-based population: a cross-sectional study.Lipids in health and disease · 2021Article
- Exome-Wide Association Study Identifies East Asian-Specific Missense VariantFrontiers in genetics · 2021Article
- The association between plasma homocysteine level and metabolic syndrome. A record-based study of Saudi patients attending King Abdulaziz Medical City in Riyadh, Saudi Arabia.Saudi medical journal · 2020Article
- Kidney function predicts the risk of asymptomatic peripheral arterial disease in a Chinese community-based population.International urology and nephrology · 2020Article
- Modification of Platelet Count on the Association between Homocysteine and Blood Pressure: A Moderation Analysis in Chinese Hypertensive Patients.International journal of hypertension · 2020Article
- Joint Effects of Plasma Homocysteine Concentration and Traditional Cardiovascular Risk Factors on the Risk of New-Onset Peripheral Arterial Disease.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Association between homocysteine level and blood pressure traits among Tibetans: A cross-sectional study in China.Medicine · 2019Article
- Pulse pressure findings following upper cervical care: a practice-based observational study.The Journal of the Canadian Chiropractic Association · 2019Article
- Association between plasma homocysteine and hypertension: Results from a cross-sectional and longitudinal analysis in Beijing's adult population from 2012 to 2017.Journal of clinical hypertension (Greenwich, Conn.) · 2018Article
- Identification of suitable reference genes for real-time qPCR in homocysteine-treated human umbilical vein endothelial cells.PloS one · 2018Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies indicated that homocysteine (Hcy) is associated with higher peripheral systolic blood pressure (pSBP). There have been few data on the relationship between Hcy and central SBP (cSBP). A total of 4,364 Chinese subjects from the Shijingshan community in Beijing were included. cSBP and pSBP were measured with an Omron HEM-9000AI device. Subjects were 57.20 ± 8.9 years old, 37.9% were male. The median of Hcy was 11.96 μmol/L. The mean of cSBP and pSBP was 129.94 ± 18.03 mmHg and 133.25 ± 18.58 mmHg. lnHcy was associated with cSBP (adjusted β = 2.17, SE = 0.80, P = 0.007) and pSBP (adjusted β = 2.42, SE = 0.75, P = 0.001). With increasing Hcy, there were enhanced correlations of Hcy with pSBP and cSBP (p for trend between quartiles <0.01). Using Q1 for reference, the Q4 was associated with cSBP (adjusted β = 1.77, SE = 0.89, P = 0.047) and pSBP (adjusted β = 2.15, SE = 0.84, P = 0.011). The correlations were more significant in non-obese subjects than in obese subjects (cSBP: β = 4.30 vs 0.46, pSBP: β = 5.04 vs 1.18, P for interaction <0.001). Our study showed that Hcy was associated with higher cSBP and pSBP, especially in non-obese subjects.
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