Evidence map›Paper›PMID 28753953›Full record

ReviewInternational journal of molecular sciences2017

Unravelling the Role of Metallothionein on Development, Reproduction and Detoxification in the Wall Lizard Podarcis sicula.

Rosaria Scudiero, Mariailaria Verderame, Chiara Maria Motta, Palma Simoniello

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rosaria ScudieroDepartment of Biology, University Federico II, Via Mezzocannone 8, 80134 Napoli, Italy. rosaria.scudiero@unina.it.
Mariailaria VerderameDepartment of Biology, University Federico II, Via Mezzocannone 8, 80134 Napoli, Italy. ilaria.verderame@unina.it.
Chiara Maria MottaDepartment of Biology, University Federico II, Via Mezzocannone 8, 80134 Napoli, Italy. chiaramaria.motta@unina.it.
Palma SimonielloDepartment of Sciences and Technology, University Parthenope, Centro Direzionale, Isola C4, 80143 Napoli, Italy. palma.simoniello@uniparthenope.it.
Federico II University Hospital · ITParthenope University of Naples · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metallothioneins (MTs) are an evolutionary conserved multigene family of proteins whose role was initially identified in binding essential metals. The physiological role of MT, however, has been revealed to be more complex than expected, since not only are MTs able to bind to toxic heavy metals, but many isoforms have shown specialized and alternative functions. Within this uncertainty, the information available on MTs in non-mammalian vertebrates, particularly in neglected tetrapods such as the reptiles, is even more scant. In this review, we provide a summary of the current understanding on metallothionein presence and function in the oviparous lizard

Indexed as

AnimalsCadmiumFemaleGene Expression Regulation, DevelopmentalLizardsMetallothioneinOrgan SpecificityOviparityReproductionCadmiumMetallothioneincadmiumembryonic developmentgene expressionin situ hybridisationoogenesisPodarcis sicula metallothioneinspermatogenesis

Identifiers

PMID28753953
PMCPMC5536057
OpenAlexW2736962791

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.