ArticleJournal of clinical laboratory analysis2018
A study on the biological reference interval of urinary alpha 1-microglobulin in a group of Chinese people.
Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Tubular dysfunction in stable adult sickle cell patients in Kinshasa: prevalence and associated factors - a cross-sectional study.Renal failure · 2026Article
- The relationship between kidney function and the soluble (pro)renin receptor in young adults: the African-PREDICT study.BMC nephrology · 2025Article
- Urinary Alpha1-Microglobulin: A New Predictor for In-Hospital Mortality in Patients with ST-Segment Elevation Myocardial Infarction.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- A study on the biological reference interval of urinary alpha 1-microglobulin in a group of Chinese people.Journal of clinical laboratory analysis · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to explore the possible influences of age and gender on urinary Alpha 1-Microglobulin (α1-MG) concentrations and establish specific reference values of urinary α1-MG in a group of healthy adults.
methodsTwo hundred and ninety-nine adults (141 males and 158 females) aged 20-60 were selected and grouped by gender and age. Urinary levels of α1-MG were detected in morning spot-urine samples, and statistical analysis was performed to explore the association between urinary α1-MG and clinical parameters, and the differences between groups were compared. The 95th percentile of distribution was used as the normal upper limit.
resultsThe value of urinary α1-MG was sex-dependent (P<0.001), the 95th percentile of urinary α1-MG of males was 26.4 mg/L, whereas females was 8.6 mg/L. Whereas urinary α1-microglobulin-to-creatinine ratio (α1-MG/Cr) was both gender-and age-dependent (both P<0.001), and age 30 may be the cut-off point in this study. The 95th percentile of males and females aged 20-30 was 16.9 mg/g, of males aged 31-60 was 19.8 mg/g, of females aged 31-60 was 28.5 mg/g. DISCUSSIONS: The relationship between urinary α1-MG concentrations and gender, age is different from previous studies. It is recommended that hospitals and laboratories should develop their own α1-MG reference intervals based on their experimental conditions.
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