Evidence map›Paper›PMID 28798202›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2017

Aerobic exercise elevates markers of angiogenesis and macrophage IL-6 gene expression in the subcutaneous adipose tissue of overweight-to-obese adults.

Douglas W Van Pelt, Lisa M Guth, Jeffrey F Horowitz

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 60 citations in OpenAlex.

  1. Trial
  2. Exercise Training Reduces the Inflammatory Response and Promotes Intestinal Mucosa-Associated Immunity in Lynch Syndrome.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Multitissue responses to exercise: a MoTrPAC feasibility study.Journal of applied physiology (Bethesda, Md. : 1985) · 2023
    Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Douglas W Van PeltSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan.ORCID http://orcid.org/0000-0001-9594-604X
Lisa M GuthSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan.
Jeffrey F HorowitzSubstrate Metabolism Laboratory, School of Kinesiology, University of Michigan, Ann Arbor, Michigan jeffhoro@umich.edu.
University of Michigan · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Karen Eileen Peterson · 2010 to 2026
$20.3M
Insulin sensitivity and fatty acid partitioning in skeletal muscle after exerciseR01DK077966 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOROWITZ, JEFFREY F · 2010 to 2020
$4.9M
NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R01 DK077966
6 · The paper itself

Abstract

Alterations in the inflammatory state, metabolic function, and structure of subcutaneous adipose tissue (SAT) can impact the development of insulin resistance in obesity. Exercise can improve metabolic health in obesity, but the effects of exercise on SAT are not well known. The purpose of this study was to examine the effects of acute exercise and habitual exercise training on mRNA expression of markers of lipid metabolism, inflammation, fibrosis, and hypoxia/angiogenesis in SAT, as well as adipocyte cell size. We recruited overweight-to-obese adults who exercised regularly (ACTIVE:

Indexed as

ExerciseNeovascularization, PhysiologicAdultCardiorespiratory FitnessFemaleHumansInflammation MediatorsInterleukin-6Lipopolysaccharide ReceptorsMacrophagesMaleObesityPlatelet Endothelial Cell Adhesion Molecule-1Sedentary BehaviorSubcutaneous FatUp-RegulationIL6 protein, humanInflammation MediatorsInterleukin-6Lipopolysaccharide ReceptorsPlatelet Endothelial Cell Adhesion Molecule-1Vascular Endothelial Growth Factor AVEGFA protein, humanadipose tissueangiogenesisexerciseinflammationmetabolic health

Identifiers

PMID28798202
PMCPMC5792100
OpenAlexW2742449100

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.