ArticlePakistan journal of medical sciences
Effects of blood lipid stability on progression of carotid atherosclerosis.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 2 citations in OpenAlex.
- Protective effect of Salvianolic acid B against atherosclerosis: a preclinical systematic review and meta-analysis.Frontiers in pharmacology · 2025Article
- Frequency of silent carotid artery stenosis in diabetics and its associated factors: An analysis in tertiary care hospital.Pakistan journal of medical sciencesArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
objectiveTo evaluate the effects of blood lipid stability on progression of carotid atherosclerosis.
methodsA total of 416 patients who had physical examination in our hospital annually from January 2010 to December 2015 were selected and divided into a progression group (n=216) and a non-progression group (n=200) according to the intima-media thickness measured by carotid ultrasound. The levels of lipid-related parameters within five years were retrospectively analyzed to calculate the smoothness index (SI = x±/s).
resultsThe cross-sectional TG, HDL-C, ApoAI, ApoB, ApoE and Lpa levels were similar in the two groups (p>0.05). The non-progression group had significantly higher TC ((4.15±0.82 vs. 4.50±1.04) mmol/L) and LDL-C ((2.53±0.76 vs. 2.99±1.03) mmol/L) levels than those of the progression group (p<0.05). The progression group had significantly lower TC SI (5.29±1.28 vs. 5.65±1.76), TG SI (2.13±0.71 vs. 2.79±0.82), LDL-C SI (3.66±1.17 vs. 4.36±1.58), ApoB SI (3.37±0.88 vs. 3.62±0.95) and Lpa SI (1.53±0.49 vs. 1.62±0.43) than those of the non-progression group (p<0.05).
conclusionCompared with cross-sectional results, SI was better correlated with the progression of atherosclerosis. The progression group had lower SI values.
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