Evidence map›Paper›PMID 28820443›Full record

ArticleNutrients2017

Omega 3 Polyunsaturated Fatty Acids Improve Endothelial Dysfunction in Chronic Renal Failure: Role of eNOS Activation and of Oxidative Stress.

Michela Zanetti, Gianluca Gortan Cappellari, Davide Barbetta, Annamaria Semolic, Rocco Barazzoni

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 45 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Observational
  9. Article
  10. Nutrients · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Frontiers in pharmacology · 2021
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michela ZanettiDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy. zanetti@units.it.
Gianluca Gortan CappellariDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy. gigici2@iol.it.
Davide BarbettaAnimal Facility, University of Trieste, 34127 Trieste, Italy. davidebarbetta68@gmail.com.
Annamaria SemolicDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy. semolic@units.it.
Rocco BarazzoniDepartment of Medical, Surgical and Health Sciences, University of Trieste, 34149 Trieste, Italy. barazzon@units.it.
University of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndothelial dysfunction is a key vascular alteration in chronic kidney disease (CKD). Omega 3 (

methods5/6 nephrectomized male Wistar rats (CKD;

resultsCompared to SHAM, in CKD aortas EDD and eNOS expression were reduced (

conclusionCollectively, these findings indicate that

Indexed as

Oxidative StressAnimalsAorta, ThoracicBiomarkersEndothelium, VascularFatty Acids, Omega-3Kidney Failure, ChronicMaleNADPH Oxidase 4NADPH OxidasesNitric OxideNitric Oxide Synthase Type IIIRatsRats, WistarTyrosine3-nitrotyrosineBiomarkersFatty Acids, Omega-3NADPH Oxidase 4NADPH OxidasesNitric OxideNitric Oxide Synthase Type IIINos3 protein, ratNox4 protein, ratTyrosineendothelial dysfunctionnitric oxideomega 3 PUFArenal diseasesuperoxide

Identifiers

PMID28820443
PMCPMC5579688
OpenAlexW2748394916

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.