Evidence map›Paper›PMID 28835449›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2017

Fluorescence quenching by metal centered porphyrins and poryphyrin enzymes.

Kenneth R Olson, Yan Gao, Faihaan Arif, Kanika Arora, Shivali Patel, Eric DeLeon, Karl D Straub

Abstract read
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. In Situ Localization ofPathogens (Basel, Switzerland) · 2024
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  10. American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
  11. Looking Back on Seven Years ofAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kenneth R OlsonIndiana University School of Medicine-South Bend Center, South Bend, Indiana; kolson@nd.edu.
Yan GaoIndiana University School of Medicine-South Bend Center, South Bend, Indiana.
Faihaan ArifIndiana University School of Medicine-South Bend Center, South Bend, Indiana.
Kanika AroraIndiana University School of Medicine-South Bend Center, South Bend, Indiana.
Shivali PatelIndiana University School of Medicine-South Bend Center, South Bend, Indiana.
Eric DeLeonIndiana University School of Medicine-South Bend Center, South Bend, Indiana.
Karl D StraubCentral Arkansas Veterans Healthcare System, Little Rock, Arkansas; and.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorescence spectroscopy and microscopy have been used extensively to monitor biomolecules, especially reactive oxygen species (ROS) and, more recently, reactive sulfide (RSS) species. Nearly all fluorophores are either excited by or emit light between 450 and 550 nm, which is similar to the absorbance of heme proteins and metal-centered porphyrins. Here we examined the effects of catalase (Cat), reduced and oxidized hemoglobin (Hb and metHb), albumin (alb), manganese (III) tetrakis (4-benzoic acid) porphyrin chloride (MnTBAP), iron protoporphyrin IX (hemin), and copper protoporphyrin IX (CuPPIX) on the fluorescence properties of fluorescein. We also examined the effects of catalase and MnTBAP on fluorophores for ROS (dichlorofluorescein, DCF), polysulfides (3',6'-di(

Indexed as

CatalaseEnzyme ActivationFluoresceinMaterials TestingMetalsPorphyrinsReproducibility of ResultsSensitivity and SpecificitySpectrometry, FluorescenceCatalaseFluoresceinMetalsPorphyrinsantioxidantsfluorescent indicatorsreactive sulfide speciesROS

Identifiers

PMID28835449
PMCPMC5668618

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.