Evidence map›Paper›PMID 28836738›Full record

ReviewStem cells translational medicine2017

Concise Review: Bioprinting of Stem Cells for Transplantable Tissue Fabrication.

Ashley N Leberfinger, Dino J Ravnic, Aman Dhawan, Ibrahim T Ozbolat

Abstract readReview
In one paragraph

Review in Stem cells translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Review
  2. Review
  3. Bridging the Gap Between Static Histology and Dynamic Organ-on-a-Chip Models.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. 3D Bioprinting for Next-Generation Personalized Medicine.International journal of molecular sciences · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ashley N LeberfingerDepartment of Surgery, Hershey, Pennsylvania, USA.
Dino J RavnicDepartment of Surgery, Hershey, Pennsylvania, USA.
Aman DhawanDepartment of Orthopedic Surgery, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
Ibrahim T OzbolatDepartment of Engineering Science and Mechanics, Pennsylvania, USA.ORCID 0000-0001-8328-4528

Funding

Career Development Program in Women's Health Research at Penn StateK12HD055882 · NICHD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI WEISMAN, CAROL S · 2007 to 2016
$4.7M
NICHD NIH HHS K12 HD055882
6 · The paper itself

Abstract

Bioprinting is a quickly progressing technology, which holds the potential to generate replacement tissues and organs. Stem cells offer several advantages over differentiated cells for use as starting materials, including the potential for autologous tissue and differentiation into multiple cell lines. The three most commonly used stem cells are embryonic, induced pluripotent, and adult stem cells. Cells are combined with various natural and synthetic materials to form bioinks, which are used to fabricate scaffold-based or scaffold-free constructs. Computer aided design technology is combined with various bioprinting modalities including droplet-, extrusion-, or laser-based bioprinting to create tissue constructs. Each bioink and modality has its own advantages and disadvantages. Various materials and techniques are combined to maximize the benefits. Researchers have been successful in bioprinting cartilage, bone, cardiac, nervous, liver, and vascular tissues. However, a major limitation to clinical translation is building large-scale vascularized constructs. Many challenges must be overcome before this technology is used routinely in a clinical setting. Stem Cells Translational Medicine 2017;6:1940-1948.

Indexed as

AnimalsBioprintingHumansRegenerative MedicineStem Cell TransplantationTissue EngineeringTissue TransplantationArtificial organsBioprintingStem cellsTissue engineeringTransplantation

Identifiers

PMID28836738
PMCPMC6430045

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.