ArticleCritical reviews in immunology2016
The Role of the Transcription Factor Ets1 in Lupus and Other Autoimmune Diseases.
Article in Critical reviews in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 43 citations in OpenAlex.
- Connecting polygenic disease risk to cell states and regulatory programs through single-cell chromatin accessibility.bioRxiv : the preprint server for biology · 2026Article
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- Comparison of cell type and disease subset chromatin modifications in SLE.Clinical epigenetics · 2024Article
- Sequences within and upstream of the mouse Ets1 gene drive high level expression in B cells, but are not sufficient for consistent expression in T cells.bioRxiv : the preprint server for biology · 2024Article
- Molecular subtypes explain lupus epigenomic heterogeneity unveiling new regulatory genetic risk variants.NPJ genomic medicine · 2024Article
- A Non-Coding Variant inFrontiers in lupus · 2023Article
- Ets1 and IL17RA cooperate to regulate autoimmune responses and skin immunity toFrontiers in immunology · 2023Article
- Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus.Nature immunology · 2022Article
- WhichTF is functionally important in your open chromatin data?PLoS computational biology · 2022Article
- NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy.The Journal of experimental medicine · 2022Article
- Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types.PLoS genetics · 2022Article
- Toll-like Receptor Signaling Inhibitory Peptide Improves Inflammation in Animal Model and Human Systemic Lupus Erythematosus.International journal of molecular sciences · 2021Article
- Association of microRNA-34a rs2666433 (A/G) Variant with Systemic Lupus Erythematosus in Female Patients: A Case-Control Study.Journal of clinical medicine · 2021Article
- Review
- A Computational Model of the Endothelial to Mesenchymal Transition.Frontiers in genetics · 2020Article
- Ets1 Controls the Development of B Cell Autoimmune Responses in a Cell-Intrinsic Manner.ImmunoHorizons · 2019Article
- Extrafollicular responses in humans and SLE.Immunological reviews · 2019Review
- SNP rs4937333 in the miRNA-5003-Binding Site of theFrontiers in genetics · 2019Article
- Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils.Clinical immunology (Orlando, Fla.) · 2018Article
- Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis.BMC medical genomics · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by excess B- and T-cell activation, the development of autoantibodies against self-antigens including nuclear antigens, and immune complex deposition in target organs, which triggers an inflammatory response and tissue damage. The genetic and environmental factors that contribute to the development of SLE have been studied extensively in both humans and mouse models of the disease. One of the important genetic contributions to SLE development is an alteration in the expression of the transcription factor Ets1, which regulates the functional differentiation of lymphocytes. Here, we review the genetic, biochemical, and immunological studies that have linked low levels of Ets1 to aberrant lymphocyte differentiation and to the pathogenesis of SLE.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.