Evidence map›Paper›PMID 28852499›Full record

ArticleJournal of animal science and biotechnology2017

Candidate genes for male and female reproductive traits in Canchim beef cattle.

Marcos Eli Buzanskas, Daniela do Amaral Grossi, Ricardo Vieira Ventura, Flavio Schramm Schenkel, Tatiane Cristina Seleguim Chud, Nedenia Bonvino Stafuzza, Luciana Diniz Rola, Sarah Laguna Conceição Meirelles, Fabiana Barichello Mokry, Maurício de Alvarenga Mudadu and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of animal science and biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
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  3. Genome-wide association study identifies significant SNPs for milk production and stature traits in Karan Fries cattle.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 2 countries.

Marcos Eli BuzanskasDepartamento de Zootecnia, Universidade Federal da Paraíba (UFPB), Areia, Paraíba 58397-000 Brazil.ORCID 0000-0002-2728-079X
Daniela do Amaral GrossiFast Genetics, Saskatoon, SK S7K 2K6 Canada.
Ricardo Vieira VenturaBeef Improvement Opportunities (BIO), Guelph, ON N1K 1E5 Canada.
Flavio Schramm SchenkelDepartment of Animal and Poultry Science, University of Guelph, Centre for Genetic Improvement of Livestock (CGIL), Guelph, ON N1G 2W1 Canada.
Tatiane Cristina Seleguim ChudDepartamento de Ciências Exatas, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (Unesp), Jaboticabal, São Paulo 14884-900 Brazil.
Nedenia Bonvino StafuzzaDepartamento de Ciências Exatas, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (Unesp), Jaboticabal, São Paulo 14884-900 Brazil.
Luciana Diniz RolaDepartamento de Zootecnia, Núcleo de Pesquisa e Conservação de Cervídeos, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (Unesp), Jaboticabal, São Paulo 14884-900 Brazil.
Sarah Laguna Conceição MeirellesDepartment of Animal Science, Federal University of Lavras (UFLA), Lavras, Minas Gerais 37200-000 Brazil.
Fabiana Barichello MokryDepartment of Genetics and Evolution, Federal University of São Carlos (UFSCar), São Carlos, São Paulo 13565-905 Brazil.
Maurício de Alvarenga MudaduEmbrapa Agricultural Informatics, Campinas, São Paulo 13083-886 Brazil.
Roberto Hiroshi HigaEmbrapa Agricultural Informatics, Campinas, São Paulo 13083-886 Brazil.
Marcos Vinícius Gualberto Barbosa da SilvaEmbrapa Dairy Cattle, Juiz de Fora, Minas Gerais 36038-330 Brazil.
Maurício Mello de AlencarEmbrapa Southeast Livestock, São Carlos, São Paulo 13560-970 Brazil.
Luciana Correia de Almeida RegitanoEmbrapa Southeast Livestock, São Carlos, São Paulo 13560-970 Brazil.
Danísio Prado MunariDepartamento de Ciências Exatas, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (Unesp), Jaboticabal, São Paulo 14884-900 Brazil.
Brazilian Agricultural Research Corporation · BRUniversidade Estadual Paulista (Unesp) · BRBIO (Canada) · CASaskatchewan Health Authority · CAUniversidade Federal da Paraíba · BRUniversidade Federal de Lavras · BRUniversidade Federal de São Carlos · BRUniversity of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBeef cattle breeding programs in Brazil have placed greater emphasis on the genomic study of reproductive traits of males and females due to their economic importance. In this study, genome-wide associations were assessed for scrotal circumference at 210 d of age, scrotal circumference at 420 d of age, age at first calving, and age at second calving, in Canchim beef cattle. Data quality control was conducted resulting in 672,778 SNPs and 392 animals.

resultsAssociated SNPs were observed for scrotal circumference at 420 d of age (435 SNPs), followed by scrotal circumference at 210 d of age (12 SNPs), age at first calving (six SNPs), and age at second calving (four SNPs). We investigated whether significant SNPs were within genic or surrounding regions. Biological processes of genes were associated with immune system, multicellular organismal process, response to stimulus, apoptotic process, cellular component organization or biogenesis, biological adhesion, and reproduction.

conclusionsFew associations were observed for scrotal circumference at 210 d of age, age at first calving, and age at second calving, reinforcing their polygenic inheritance and the complexity of understanding the genetic architecture of reproductive traits. Finding many associations for scrotal circumference at 420 d of age in various regions of the Canchim genome also reveals the difficulty of targeting specific candidate genes that could act on fertility; nonetheless, the high linkage disequilibrium between loci herein estimated could aid to overcome this issue. Therefore, all relevant information about genomic regions influencing reproductive traits may contribute to target candidate genes for further investigation of causal mutations and aid in future genomic studies in Canchim cattle to improve the breeding program.

Indexed as

Animal breedingComposite breedGenome-wide associationGenomic dataSingle nucleotide polymorphism

Identifiers

PMID28852499
PMCPMC5569548
OpenAlexW2747577323

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.