Evidence map›Paper›PMID 28855862›Full record

ArticleFrontiers in cellular neuroscience2017

Novel Influences of IL-10 on CNS Inflammation Revealed by Integrated Analyses of Cytokine Networks and Microglial Morphology.

Warren D Anderson, Andrew D Greenhalgh, Aditya Takwale, Samuel David, Rajanikanth Vadigepalli

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  5. Modulation of microglial activation by antidepressants.Journal of psychopharmacology (Oxford, England) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Warren D AndersonDaniel Baugh Institute for Functional Genomics/Computational Biology, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson UniversityPhiladelphia, PA, United States.
Andrew D GreenhalghCenter for Research in Neuroscience, The Research Institute of the McGill University Health CenterMontreal, QC, Canada.
Aditya TakwaleCenter for Research in Neuroscience, The Research Institute of the McGill University Health CenterMontreal, QC, Canada.
Samuel DavidCenter for Research in Neuroscience, The Research Institute of the McGill University Health CenterMontreal, QC, Canada.
Rajanikanth VadigepalliDaniel Baugh Institute for Functional Genomics/Computational Biology, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson UniversityPhiladelphia, PA, United States.
McGill University Health Centre · CAThomas Jefferson University · US

Funding

BASIC CARDIOVASCULAR RESEARCH TRAINING GRANTT32HL007284 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Brant E Isakson, Gary K Owens · 1985 to 2026
$19.6M
Modeling Central Autonomic Regulatory Network Adaptation to HypertensionR01HL111621 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI SCHWABER, JAMES, VADIGEPALLI, RAJANIKANTH · 2012 to 2015
$2.4M
NHLBI NIH HHS R01 HL111621NHLBI NIH HHS T32 HL007284
6 · The paper itself

Abstract

Coordinated interactions between cytokine signaling and morphological dynamics of microglial cells regulate neuroinflammation in CNS injury and disease. We found that pro-inflammatory cytokine gene expression

Indexed as

CNS inflammationcytokine adaptationIL-10microglia morphologyTNFα

Identifiers

PMID28855862
PMCPMC5557777
OpenAlexW2744368122

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.