Evidence mapPaperPMID 28860169Full record

Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2018

Creatine ( methyl-d

Richard V Clark, Ann C Walker, Ram R Miller, Robin L O'Connor-Semmes, Eric Ravussin, William T Cefalu

Open access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 64 citations in OpenAlex.

  1. Application of the DJournal of cachexia, sarcopenia and muscle · 2023
    Trial
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. What Is 'Muscle Health'? A Narrative Review and Conceptual Framework.Journal of functional morphology and kinesiology · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Estimating Muscle Mass Using D3-Creatine Dilution: A Narrative Review of Clinical Implications and Comparison With Other Methods.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Skeletal muscle mass can be estimated by creatine (methyl-dEuropean journal of clinical nutrition · 2023
    Article
  20. DJournal of cachexia, sarcopenia and muscle · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Richard V ClarkMuscle Metabolism Discovery Performance Unit, GlaxoSmithKline, Research Triangle Park, North Carolina.
Ann C WalkerMuscle Metabolism Discovery Performance Unit, GlaxoSmithKline, Research Triangle Park, North Carolina.
Ram R MillerMuscle Metabolism Discovery Performance Unit, GlaxoSmithKline, Research Triangle Park, North Carolina.
Robin L O'Connor-SemmesMuscle Metabolism Discovery Performance Unit, GlaxoSmithKline, Research Triangle Park, North Carolina.
Eric RavussinPennington Biomedical Research Center , Baton Rouge, Louisiana.
William T CefaluPennington Biomedical Research Center , Baton Rouge, Louisiana.
Research Triangle Park Foundation · USPennington Biomedical Research Center · US

Funding

Pilot and Feasibility ProgramP30DK072476 · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · 2005 to 2025
$2.2M
NIDDK NIH HHS P30 DK072476
6 · The paper itself

Abstract

A noninvasive method to estimate muscle mass based on creatine ( methyl-d

Indexed as

Body CompositionIndicator Dilution TechniquesMuscle, SkeletalAbsorptiometry, PhotonAgedAged, 80 and overCreatineDeuteriumFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedCreatineDeuteriumcreatinecreatininedual-energy X-ray absorptiometrylean massmuscle mass

Identifiers

PMID28860169
PMCPMC6048459
OpenAlexW2753273790

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.