Evidence map›Paper›PMID 28864499›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2017

Ethanol metabolism by alcohol dehydrogenase or cytochrome P

Erin E Doody, Jennifer L Groebner, Jetta R Walker, Brittnee M Frizol, Dean J Tuma, David J Fernandez, Pamela L Tuma

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  15. Review
  16. The hepato-protective effect of eupatilin on an alcoholic liver disease model of rats.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2020
    Article
  17. Antioxidants (Basel, Switzerland) · 2020
    Article
  18. Article
  19. Alcohol-induced microtubule acetylation leads to the accumulation of large, immobile lipid droplets.American journal of physiology. Gastrointestinal and liver physiology · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Erin E DoodyDepartment of Biology, The Catholic University of America, Washington, District of Columbia.
Jennifer L GroebnerDepartment of Biology, The Catholic University of America, Washington, District of Columbia.
Jetta R WalkerNorthern Virginia Community College, Alexandria, Virginia; and.
Brittnee M FrizolDepartment of Biology, The Catholic University of America, Washington, District of Columbia.
Dean J TumaDepartment of Internal Medicine, University of Nebraska, Omaha, Nebraska.
David J FernandezNorthern Virginia Community College, Alexandria, Virginia; and.
Pamela L TumaDepartment of Biology, The Catholic University of America, Washington, District of Columbia; tuma@cua.edu.
University of America · USNorthern Virginia Community College · USCatholic University of America · USUniversity of Nebraska at Omaha · US

Funding

Alcohol-induced changes in protein acetylation: mechanisms and consequencesR01AA017626 · NIAAA · CATHOLIC UNIVERSITY OF AMERICA · PI PAMELA L. TUMA · 2010 to 2026
$3.0M
NIAAA NIH HHS R01 AA017626
6 · The paper itself

Abstract

The liver metabolizes alcohol using alcohol dehydrogenase (ADH) and cytochrome P

Indexed as

AcetaldehydeAcetylationAlcohol DehydrogenaseAnimalsAntioxidantsBiotransformationCytochrome P-450 CYP2E1Cytochrome P-450 CYP2E1 InhibitorsEndocytosisEthanolGrowth HormoneHep G2 CellsHumansJanus Kinase 2LiverMicrotubule ProteinsAcetaldehydeAlcohol DehydrogenaseAntioxidantsCytochrome P-450 CYP2E1Cytochrome P-450 CYP2E1 InhibitorsEthanolGrowth HormoneJak2 protein, ratJanus Kinase 2Microtubule ProteinsReactive Oxygen SpeciesStat5b protein, ratSTAT5 Transcription FactorCYP2E1ethanol, hepatotoxicityWIF-B cells

Identifiers

PMID28864499
PMCPMC5814672
OpenAlexW2752117556

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.