Evidence map›Paper›PMID 28864996›Full record

ReviewInflammopharmacology2017

Immunomodulatory basis of antioxidant therapy and its future prospects: an appraisal.

Y Ajith, U Dimri, S K Dixit, Shanker K Singh, A Gopalakrishnan, E Madhesh, J B Rajesh, S G Sangeetha

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. A critical review of Ginger's (Frontiers in nutrition · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Y AjithDivision of Medicine, Indian Veterinary Research Institute, Izatnagar, UP, 243122, India. ajithy123456789@gmail.com.
U DimriDivision of Medicine, Indian Veterinary Research Institute, Izatnagar, UP, 243122, India.
S K DixitDivision of Medicine, Indian Veterinary Research Institute, Izatnagar, UP, 243122, India.
Shanker K SinghDepartment of Veterinary Medicine, College of Veterinary Science and Animal Husbandry, U.P. Pt. Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan (DUVASU), Mathura, UP, 281 001, India.
A GopalakrishnanDivision of Medicine, Indian Veterinary Research Institute, Izatnagar, UP, 243122, India.
E MadheshDivision of Medicine, Indian Veterinary Research Institute, Izatnagar, UP, 243122, India.
J B RajeshDivision of Medicine, Indian Veterinary Research Institute, Izatnagar, UP, 243122, India.
S G SangeethaDivision of Medicine, Indian Veterinary Research Institute, Izatnagar, UP, 243122, India.
Indian Veterinary Research Institute · INUttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antioxidants are agents which can modulate oxidant-antioxidant profile of body system by neutralizing pro-oxidant molecules. The current scientific knowledge on mechanisms of antioxidant activity of biomolecules was critically reviewed with a special emphasis on immunomodulation. The immuno-oxidative wreckage of animals in various disease conditions and the role of biomodulators in curbing the oxidative stress through immune pathways were analyzed. The critical role of immunomodulatory mechanisms in controlling oxidative damage was identified. Selection of antioxidant therapy considering the immunopharmacology of the drug as well as immunological basis of disease may reduce treatment failure and adverse health effects. Hence, it is suggested that future studies on antioxidants may focus on the immuno-oxidative pathobiology to better understand its clinical effects and effective disease management.

Indexed as

AntioxidantsCytokine responseImmunomodulatorsReactive oxygen speciesVeterinary medicine

Identifiers

PMID28864996
OpenAlexW2752390531

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.