Evidence mapPaperPMID 28865807Full record

ReviewMolecular and cellular endocrinology2018

Intracrine androgen biosynthesis, metabolism and action revisited.

Lina Schiffer, Wiebke Arlt, Karl-Heinz Storbeck

Open access · hybridAbstract readReview
In one paragraph

Review in Molecular and cellular endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 2 pooled it
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 2 syntheses or guidelines pooled it, 209 citations in OpenAlex.

  1. Pooled it
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  5. GPRC6A-Duox1 Axis Regulates the Hair Cycle Through HTissue engineering and regenerative medicine · 2026
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59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Lina SchifferInstitute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Wiebke ArltInstitute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK. Electronic address: w.arlt@bham.ac.uk.
Karl-Heinz StorbeckInstitute of Metabolism and Systems Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK; Department of Biochemistry, Stellenbosch University, Stellenbosch 7600, South Africa.
University of Birmingham · GBStellenbosch University · ZA

Funding

Wellcome Trust 092283
6 · The paper itself

Abstract

Androgens play an important role in metabolic homeostasis and reproductive health in both men and women. Androgen signalling is dependent on androgen receptor activation, mostly by testosterone and 5α-dihydrotestosterone. However, the intracellular or intracrine activation of C

Indexed as

AndrogensAnimalsBiosynthetic PathwaysHumansOrgan SpecificityReproductionSteroidsAndrogensSteroids11-oxygenated androgensAndrogensHormone-dependent cancerIntracrinologySteroid biosynthesisTestosterone

Identifiers

PMID28865807
PMCPMC6565845
OpenAlexW2752706152

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.