Evidence map›Paper›PMID 28867798›Full record

SynthesisNutrients2017

Vitamin C Status and Cognitive Function: A Systematic Review.

Nikolaj Travica, Karin Ried, Avni Sali, Andrew Scholey, Irene Hudson, Andrew Pipingas

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06995586 (The Synergistic Action of Vitamins and Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.), which is not on this map. Cited by 78 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 4 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06995586 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Synergistic Action of Vitamins and Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.

TypeinterventionalSponsorNicosia General HospitalRan2026 to 2028Enrolled108ConditionsCardio-pulmonary Bypass, Cardiovascular Diseases, Omega-3 Polyunsaturated Fatty Acids, Omega-3 SupplementationArmsVitamin C, Omega 3 PUFA (EPO/DHA), Lignin, Lactulose
3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 4 syntheses or guidelines pooled it, 163 citations in OpenAlex.

  1. Pooled it
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  8. Review
  9. Review
  10. Daily intake of antioxidants ameliorates PMFrontiers in nutrition · 2026
    Article
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  17. Review
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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nikolaj TravicaCentre for Human Psychopharmacology, Swinburne University of Technology, John St, Hawthorn, Melbourne 3122, Australia. ntravica@niim.com.au.
Karin RiedThe National Institute of Integrative Medicine, 21 Burwood Rd, Hawthorn, Melbourne 3122, Australia. karinried@niim.com.au.
Avni SaliThe National Institute of Integrative Medicine, 21 Burwood Rd, Hawthorn, Melbourne 3122, Australia. asali@niim.com.au.
Andrew ScholeyCentre for Human Psychopharmacology, Swinburne University of Technology, John St, Hawthorn, Melbourne 3122, Australia. andrew@scholeylab.com.
Irene HudsonCentre for Human Psychopharmacology, Swinburne University of Technology, John St, Hawthorn, Melbourne 3122, Australia. Ihudson@swin.edu.au.
Andrew PipingasCentre for Human Psychopharmacology, Swinburne University of Technology, John St, Hawthorn, Melbourne 3122, Australia. apipingas@swin.edu.au.
Swinburne University of Technology · AUNational Institute of Integrative Medicine · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin C plays a role in neuronal differentiation, maturation, myelin formation and modulation of the cholinergic, catecholinergic, and glutaminergic systems. This review evaluates the link between vitamin C status and cognitive performance, in both cognitively intact and impaired individuals. We searched the PUBMED, SCOPUS, SciSearch and the Cochrane Library from 1980 to January 2017, finding 50 studies, with randomised controlled trials (RCTs,

Indexed as

Ascorbic AcidCognition DisordersCognitive DysfunctionNutritional StatusAscorbic AcidAlzheimer’sascorbic acidcentral nervous systemcognitiondementiaMMSEvitamin C

Identifiers

PMID28867798
PMCPMC5622720
OpenAlexW2752339005

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.