Evidence map›Paper›PMID 28869251›Full record

ReviewNature reviews. Nephrology2017

Cardiac surgery-associated acute kidney injury: risk factors, pathophysiology and treatment.

Ying Wang, Rinaldo Bellomo

5 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 348 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
348citing papers in PubMed, 10 pooled it
26.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03798067 unknown statusnot on this mapstarted 2019, after this paper: background citation

Correlation Between Monitoring Renal Hemodynamics by Esophageal Ultrasound and Acute Kidney Injury After Heart Surgery.

TypeobservationalSponsorXuzhou Medical UniversityRan2019 to 2019Enrolled60ConditionsPostoperative Acute Kidney Injury
NCT04125069 completednot on this mapstarted 2019, after this paper: background citation

Role of Mitochondrial Dysfunction in the Occurrence of Acute Kidney Injury(AKI) in Postoperative Cardiac Surgery

TypeobservationalSponsorUniversity Hospital Center of MartiniqueRan2019 to 2022Enrolled27ConditionsPatients Undergoing Coronary Artery Bypass Graft (CABG) Surgery Requiring Extracorporeal CirculationArmsCoronary Artery Bypass Graft (CABG)
NCT04172103 completednot on this mapstarted 2019, after this paper: background citation

The Association Between the Duration of Acute Kidney Injury and New-onset Chronic Kidney Disease After Cardiac or Thoracic Aortic Surgery: a Retrospective Observational Cohort Study

TypeobservationalSponsorSeoul National University HospitalRan2019 to 2020Enrolled2,009ConditionsAcute Kidney Injury, Chronic Kidney Disease, Stage 3, Chronic Kidney Disease, Stage 5, Cardiac Surgery
NCT05222074 completednot on this map

Venous Congestion Rather Than Intraoperative Hypotension is Associated With Acute Adverse Kidney Events After Cardiac Surgery

TypeobservationalSponsorNanjing First Hospital, Nanjing Medical UniversityRan2016 to 2021Enrolled5,127ConditionsAcute Kidney Injury, Acute Kidney DiseaseArmsVenous congestion, Introperation hypotension
NCT06521307 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Impact of Nicotinamide Riboside (NR) on Kidney Function in Patients Undergoing Cardiac Surgery.A Randomized Controlled Pilot Study

TypeinterventionalSponsorInstituto Nacional de Cardiologia Ignacio ChavezRan2024 to 2026Enrolled100ConditionsAcute Kidney Injury, Cardiac Valve DiseaseArmsNicotinamide riboside, Placebo
3 · Its place in the literature

Who cites it

348 citing papers in PubMed, 10 syntheses or guidelines pooled it, 766 citations in OpenAlex.

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288 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ying WangThe Renal and Metabolic Division, The George Institute for Global Health, Level 5, 1 King Street, Newtown, New South Wales 2042, Australia.
Rinaldo BellomoThe Renal and Metabolic Division, The George Institute for Global Health, Level 5, 1 King Street, Newtown, New South Wales 2042, Australia.
The George Institute for Global Health · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac surgery-associated acute kidney injury (CSA-AKI) is the most common clinically important complication in adult patients undergoing open heart surgery, and is associated with increased mortality and morbidity. In patients in intensive care units, CSA-AKI is the second most common type of AKI after septic AKI. In this Review, we explore the definition of CSA-AKI, discuss its epidemiology and identify its risk factors. We discuss current theories of the pathophysiology of CSA-AKI and describe its clinical course. Furthermore, we introduce diagnostic tools with particular reference to novel biomarkers of AKI and their potential utility; we analyse currently applied interventions aimed at attenuating AKI in patients undergoing cardiac surgery; and describe evidence from randomized controlled trials aimed at preventing or treating CSA-AKI. Finally, we explore issues in the use of renal replacement therapy, its timing, its intensity and its preferred modalities in patients with CSA-AKI, and we discuss the prognosis of CSA-AKI in terms of patient survival and kidney recovery.

Indexed as

Acute Kidney InjuryPostoperative ComplicationsCardiac Surgical ProceduresGlomerular Filtration RateHumansPrognosisRenal Replacement Therapy

Identifiers

PMID28869251
OpenAlexW2751869644

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.