Evidence map›Paper›PMID 28869532›Full record

ReviewInternational journal of molecular sciences2017

CFTR-NHERF2-LPA₂ Complex in the Airway and Gut Epithelia.

Weiqiang Zhang, Zhihong Zhang, Yanhui Zhang, Anjaparavanda P Naren

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Functional Consequences of CFTR Interactions in Cystic Fibrosis.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
  6. SARS-CoV-2 (COVID-19) and cystic fibrosis.American journal of physiology. Lung cellular and molecular physiology · 2020
    Article
  7. Article
  8. Transepithelial Fluid and Salt Re-Absorption Regulated by cGK2 Signals.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Weiqiang ZhangDepartment of Pediatrics & Department of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA. wzhang16@uthsc.edu.
Zhihong ZhangDepartment of Pediatrics & Department of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA. zzhang19@uthsc.edu.
Yanhui ZhangDepartment of Bioscience research, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA. yzhang36@uthsc.edu.
Anjaparavanda P NarenDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. anaren@cchmc.org.
University of Tennessee Health Science Center · USCincinnati Children's Hospital Medical Center · US

Funding

Inhibition of an apical cAMP transporter (MRP4) in the gut induces diarrheaR01DK080834 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI Anjaparavanda P Naren · 2009 to 2026
$6.8M
LPA2 receptor-containing complexes in regulating secretory diarrheaR01DK093045 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI NAREN, ANJAPARAVANDA P · 2011 to 2019
$3.0M
Characterization of an inhibitory protein complex for cystic fibrosis therapyR01HL123535 · NHLBI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI ZHANG, WEIQIANG · 2014 to 2018
$1.9M
NHLBI NIH HHS R01 HL123535NIDDK NIH HHS R01 DK080834NIDDK NIH HHS R01 DK093045
6 · The paper itself

Abstract

The cystic fibrosis transmembrane conductance regulator (CFTR) is a cAMP- and cGMP-regulated chloride (Cl

Indexed as

AnimalsCell MembraneCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDiarrheaDrug DiscoveryEpithelial CellsHumansIntestinal MucosaMolecular Targeted TherapyMultiprotein ComplexesPhosphoproteinsProtein BindingProtein Interaction Domains and MotifsReceptors, Lysophosphatidic AcidRespiratory MucosaCystic Fibrosis Transmembrane Conductance RegulatorMultiprotein ComplexesPhosphoproteinsReceptors, Lysophosphatidic Acidsodium-hydrogen exchanger regulatory factorSodium-Hydrogen ExchangersABC transportersCFTRcystic fibrosisLPA2macromolecular protein complexNHERF2secretory diarrhea

Identifiers

PMID28869532
PMCPMC5618545
OpenAlexW2751016974

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.