ArticleViruses2017
Using Next Generation Sequencing to Identify and Quantify the Genetic Composition of Resistance-Breaking Commercial Isolates of Cydia pomonella Granulovirus.
Article in Viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Emergence of new resistances toFrontiers in physiology · 2026Article
- Crop diversity induces trade-offs in microbial biopesticide susceptibility that could delay pest resistance evolution.PLoS pathogens · 2025Article
- Baculovirus Genetic Diversity and Population Structure.Viruses · 2025Review
- Assembly and Genome Annotation of Different Strains of Apple Fruit Moth Virus (International journal of molecular sciences · 2024Article
- Viruses of the Fall ArmywormViruses · 2021Review
- CpGV-M Replication in Type I Resistant Insects: Helper Virus and Order of Ingestion Are Important.Viruses · 2021Article
- Monitoring Insect Transposable Elements in Large Double-Stranded DNA Viruses Reveals Host-to-Virus and Virus-to-Virus Transposition.Molecular biology and evolution · 2021Article
- Patterns in Genotype Composition of Indian Isolates of the Bombyx mori Nucleopolyhedrovirus and Bombyx mori Bidensovirus.Viruses · 2021Article
- Transcriptome of Cydia pomonella granulovirus in susceptible and type I resistant codling moth larvae.The Journal of general virology · 2021Article
- Population structure of Cydia pomonella granulovirus isolates revealed by quantitative analysis of genetic variation.Virus evolution · 2021Article
- Nucleopolyhedrovirus Coocclusion Technology: A New Concept in the Development of Biological Insecticides.Frontiers in microbiology · 2021Review
- Article
- Novel Diversity and Virulence Patterns Found in New Isolates of Cydia pomonella Granulovirus from China.Applied and environmental microbiology · 2020Article
- Twenty-five Years of Research Experience with the Sterile Insect Technique and Area-Wide Management of Codling Moth,Insects · 2019Review
- Cryptophlebia peltastica Nucleopolyhedrovirus Is Highly Infectious to Codling Moth Larvae and Cells.Applied and environmental microbiology · 2019Article
- Article
- Genome Analysis of A Novel South African Cydia pomonella granulovirus (CpGV-SA) with Resistance-Breaking Potential.Viruses · 2019Article
- Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of Cydia pomonella granulovirus (CpGV) isolates as biological control agents of codling moth (CM) larvae is important in organic and integrated pome fruit production worldwide. The commercially available isolates CpGV-0006, CpGV-R5, and CpGV-V15 have been selected for the control of CpGV resistant CM populations in Europe. In infection experiments, CpGV-0006 and CpGV-R5 were able to break type I resistance and to a lower extent also type III resistance, whereas CpGV-V15 overcame type I and the rarely occurring type II and type III resistance. The genetic background of the three isolates was investigated with next generation sequencing (NGS) tools by comparing their nucleotide compositions to whole genome alignments of five CpGV isolates representing the known genetic diversity of the CpGV genome groups A to E. Based on the distribution of single nucleotide polymorphisms (SNPs) in Illumina sequencing reads, we found that the two isolates CpGV-0006 and CpGV-R5 have highly similar genome group compositions, consisting of about two thirds of the CpGV genome group E and one third of genome group A. In contrast, CpGV-V15 is composed of equal parts of CpGV genome group B and E. According to the identified genetic composition of these isolates, their efficacy towards different resistance types can be explained and predictions on the success of resistance management strategies in resistant CM populations can be made.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.