Evidence map›Paper›PMID 28878053›Full record

ArticleNeurology2017

Subjective memory complaints in preclinical autosomal dominant Alzheimer disease.

Daniel J Norton, Rebecca Amariglio, Hillary Protas, Kewei Chen, Daniel C Aguirre-Acevedo, Brendan Pulsifer, Gabriel Castrillon, Victoria Tirado, Claudia Munoz, Pierre Tariot and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Associations Among Loneliness, Purpose in Life and Subjective Cognitive Decline in Ethnoracially Diverse Older Adults Living in the United States.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2023
    Article
  7. Article
  8. Article
  9. Dementia in Latin America: Paving the way toward a regional action plan.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Spermidine/spermine-NAlzheimer's research & therapy · 2019
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Daniel J NortonFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Rebecca AmariglioFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Hillary ProtasFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Kewei ChenFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Daniel C Aguirre-AcevedoFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Brendan PulsiferFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Gabriel CastrillonFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Victoria TiradoFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Claudia MunozFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Pierre TariotFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Jessica B LangbaumFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Eric M ReimanFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Francisco LoperaFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Reisa A SperlingFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA.
Yakeel T QuirozFrom Massachusetts General Hospital (D.J.N., R.A., B.P., R.A.S., Y.T.Q.); Harvard Medical School (D.J.N., R.A., R.A.S., Y.T.Q.); Center for Alzheimer Research and Treatment, Brigham and Women's Hospital (R.A., R.A.S.), Boston, MA; Banner Alzheimer's Institute (H.P., K.C., P.T., J.B.L., E.M.R.), Phoenix, AZ; Grupo de Neurociencias (D.C.A.-A., V.T., C.M., F.L., Y.T.Q.), Universidad de Antioquia; Instituto de Alta Tecnologia Medica (G.C.), Medellin, Colombia; and Athinoula A Martinos Center for Biomedical Imaging (Y.T.Q.), Boston, MA. yquiroz@mgh.harvard.edu.

Funding

Alzheimer's Disease Neuroimaging InitiativeU01AG024904 · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · 2004 to 2005
$21.3M
TAU ALTERATIONS IN ALZHEIMER'S AND RELATED DEMENTIASP50AG005134 · MASSACHUSETTS GENERAL HOSPITAL · 1985 to 2005
$12.3M
NIA NIH HHS K23 AG044431NIA NIH HHS K24 AG035007NIA NIH HHS P50 AG005134NIA NIH HHS R01 AG027435NIA NIH HHS R01 AG034556NIA NIH HHS R01 AG037497NIA NIH HHS R01 AG055444NIA NIH HHS U01 AG024904NIA NIH HHS U01 AG032438NIA NIH HHS U19 AG010483NIH HHS DP5 OD019833
6 · The paper itself

Abstract

objectiveTo cross-sectionally study subjective memory complaints (SMC) in autosomal dominant Alzheimer disease (ADAD).

methodsWe examined self-reported and study partner-based SMC in 52 young, cognitively unimpaired individuals from a Colombian kindred with early-onset ADAD. Twenty-six carried the

resultsSelf-reported SMC were greater in carriers than noncarriers (

conclusionsCognitively unimpaired

Indexed as

AdultAge FactorsAlzheimer DiseaseCognition DisordersCross-Sectional StudiesFemaleHippocampusHumansImaging, Three-DimensionalMagnetic Resonance ImagingMaleMemory DisordersMiddle AgedNeuropsychological TestsPolymorphism, Single NucleotidePresenilin-1Presenilin-1

Identifiers

PMID28878053
PMCPMC5631170

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.