Evidence map›Paper›PMID 28878733›Full record

ReviewFrontiers in neurology2017

Clinical Approach to Supranuclear Brainstem Saccadic Gaze Palsies.

Alexandra Lloyd-Smith Sequeira, John-Ross Rizzo, Janet C Rucker

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Spectrum of Pediatric to Early AdulthoodMovement disorders clinical practice · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Progressive Supranuclear Palsy: an Update.Current neurology and neuroscience reports · 2018
    Review
  12. Neuro-Ophthalmology at the Bedside: A Clinical Guide.Journal of neurosciences in rural practice
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alexandra Lloyd-Smith SequeiraDepartment of Neurology, New York University School of Medicine, New York, NY, United States.
John-Ross RizzoDepartment of Neurology, New York University School of Medicine, New York, NY, United States.
Janet C RuckerDepartment of Neurology, New York University School of Medicine, New York, NY, United States.
New York University · US

Funding

Rehabilitation Medicine Scientist Training (RMST) ProgramK12HD001097 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BONINGER, MICHAEL L. · 1995 to 2016
$14.1M
NICHD NIH HHS K12 HD001097
6 · The paper itself

Abstract

Failure of brainstem supranuclear centers for saccadic eye movements results in the clinical presence of a brainstem-mediated supranuclear saccadic gaze palsy (SGP), which is manifested as slowing of saccades with or without range of motion limitation of eye movements and as loss of quick phases of optokinetic nystagmus. Limitation in the range of motion of eye movements is typically worse with saccades than with smooth pursuit and is overcome with vestibular-ocular reflexive eye movements. The differential diagnosis of SGPs is broad, although acute-onset SGP is most often from brainstem infarction and chronic vertical SGP is most commonly caused by the neurodegenerative condition progressive supranuclear palsy. In this review, we discuss the brainstem anatomy and physiology of the brainstem saccade-generating network; we discuss the clinical features of SGPs, with an emphasis on insights from quantitative ocular motor recordings; and we consider the broad differential diagnosis of SGPs.

Indexed as

burst neuronprogressive supranuclear palsysaccadesslow saccadessupranuclear

Identifiers

PMID28878733
PMCPMC5572401
OpenAlexW2748526008

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.