Evidence map›Paper›PMID 28887409›Full record

ArticleDiabetes care2017

Longitudinal Change in Fasting Blood Glucose and Myocardial Infarction Risk in a Population Without Diabetes.

Cheng Jin, Shuohua Chen, Anand Vaidya, Yuntao Wu, Zhijun Wu, Frank B Hu, Penny Kris-Etherton, Shouling Wu, Xiang Gao

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 258 citations in OpenAlex.

  1. Trial
  2. Ten-year trajectory of Life's Essential 8 and aortic valve calcification.American journal of preventive cardiology · 2026
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  20. Time in target range for systolic blood pressure and glucose with cardiovascular disease and all-cause mortality risks.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Cheng JinDepartment of Cardiology, Kailuan General Hospital, Tangshan, People's Republic of China.
Shuohua ChenDepartment of Cardiology, Kailuan General Hospital, Tangshan, People's Republic of China.
Anand VaidyaDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Yuntao WuDepartment of Cardiology, Kailuan General Hospital, Tangshan, People's Republic of China.
Zhijun WuDepartment of Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Frank B HuDepartments of Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Penny Kris-EthertonDepartment of Nutritional Sciences, The Pennsylvania State University, State College, PA.
Shouling WuDepartment of Cardiology, Kailuan General Hospital, Tangshan, People's Republic of China.
Xiang GaoDepartment of Nutritional Sciences, The Pennsylvania State University, State College, PA xxg14@psu.edu drwusl@163.com.ORCID 0000-0003-2617-6509
Kailuan General Hospital · CNPennsylvania State University · USBrigham and Women's Hospital · USHarvard University · USShanghai Jiao Tong University · CN

Funding

Interactions Between Adrenal and Parathyroid Hormones in Human HealthR01DK107407 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI VAIDYA, ANAND · 2015 to 2019
$2.5M
Vitamin D and Hormonal Mechanisms of Cardiovascular Disease in ObesityK23HL111771 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI VAIDYA, ANAND · 2012 to 2016
$805k
Statins, statin-related gene, and Parkinson's disease riskR21NS087235 · NINDS · PENNSYLVANIA STATE UNIVERSITY, THE · PI GAO, XIANG · 2014 to 2015
$398k
NHLBI NIH HHS K23 HL111771NIDDK NIH HHS R01 DK107407NINDS NIH HHS R21 NS087235
6 · The paper itself

Abstract

objectiveTo examine the change in fasting blood glucose (FBG) during repeated assessments over time and its potential impact on the risk of developing myocardial infarction (MI). RESEARCH DESIGN AND

methodsThis prospective cohort study included 68,297 participants without diabetes (mean age 49 years) who were free of MI, stroke, and cancer prior to or in 2010 (baseline of the current analysis). FBG concentrations were measured in 2006, 2008, and 2010. The FBG trajectories during 2006-2010, the primary exposure of the current study, were identified by latent mixture modeling. Incident MI cases were confirmed via review of medical records by cardiologists.

resultsWe identified five discrete FBG trajectories according to FBG range and changing pattern over time: elevated-stable (

conclusionsWe found that discrete FBG trajectories were significantly associated with subsequent risk of MI in individuals without diabetes. These observations suggest that long-term trajectories of FBG may be important for risk prediction of MI and possibly other macrovascular diseases.

Indexed as

FastingAdolescentAdultAgedAged, 80 and overBlood GlucoseCholesterolC-Reactive ProteinDiabetes MellitusFemaleFollow-Up StudiesHumansIncidenceLife StyleMaleMiddle AgedBlood GlucoseCholesterolC-Reactive ProteinTriglycerides

Identifiers

PMID28887409
PMCPMC5652588
OpenAlexW2750614861

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.