Evidence mapPaperPMID 28894848Full record

ReviewEuropean journal of breast health2017

Risk Reduction Strategies in Breast Cancer Prevention.

Mauricio Costa, Paula Saldanha

Registry-linked trialOpen access · diamondAbstract readReview
In one paragraph

Review in European journal of breast health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05570266 (Genetic and Non-Genetic Breast Cancer Risk Prediction Evaluation in Indonesian Samples), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05570266 completednot on this mapstarted 2020, after this paper: background citation

Genetic and Non-Genetic Breast Cancer Risk Prediction Evaluation in Indonesian Samples

Typeobservational_patient_registrySponsorNalagenetics Pte LtdRan2020 to 2023Enrolled322ConditionsBreast CancerArmsBreast Cancer Risk Prediction Software
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. The effect of vitamin D and E vaginal suppositories on tamoxifen-induced vaginal atrophy in women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019
    Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Melatonin: A Molecule for Reducing Breast Cancer Risk.Molecules (Basel, Switzerland) · 2018
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mauricio CostaAmericas Medical City, Breast Center, Rio de Janeiro, Brazil.
Paula SaldanhaAmericas Medical City, Breast Center, Rio de Janeiro, Brazil.
Breast Center · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evaluating the risk of breast cancer makes it possible to identify women with a high risk of developing breast cancer in the future. Adopting a healthier lifestyle, involving diet and exercise, is one way of reducing this risk-but there are other, non-modifiable risk factors, such as family history, genetics and diagnosis of premalignant lesions. In this high-risk population, the tracking must be rigorous and involve the participation of the patient herself, earlier and more frequent clinical assessment, and the use of imaging screening. Agents such as tamoxifen, raloxifene and aromatase inhibitors may be used in chemoprevention and may reduce the risk substantially. The risks and benefits must be assessed, and one must discuss with the patient her adverse events and the decision regarding the best treatment. Women who carry the BRCA1/2 mutation (very high risk) can benefit from prophylactic surgical interventions, such as bilateral mastectomy and/or bilateral salpingo-oophorectomy. This group of patients must be monitored by a multidisciplinary team, providing explanations prior to surgery regarding the surgical treatment offered, the reconstruction techniques, and the risks and complications.

Indexed as

Breastmastectomyriskserm oophorectomy

Identifiers

PMID28894848
PMCPMC5544140
OpenAlexW2730948960

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.