ReviewTrends in genetics : TIG2017
Playing Well with Others: Extrinsic Cues Regulate Neural Progenitor Temporal Identity to Generate Neuronal Diversity.
Review in Trends in genetics : TIG, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Steroid hormone-dependent glial-neuronal interaction promotes brain development duringbioRxiv : the preprint server for biology · 2025Article
- Spatially Organized IGF1-mTOR Signaling Controls Human Forebrain Progenitor F ate Through Coordinated Transcriptional and Translational Programs.bioRxiv : the preprint server for biology · 2025Article
- Stem cell-specific ecdysone signaling regulates the development of dorsal fan-shaped body neurons and sleep homeostasis.Current biology : CB · 2024Article
- The Drosophila neuroblast polarity cycle at a glance.Journal of cell science · 2024Article
- Stem cell-specific ecdysone signaling regulates the development and function of abioRxiv : the preprint server for biology · 2023Article
- Temporal regulation of neural diversity in Drosophila and vertebrates.Seminars in cell & developmental biology · 2023Review
- Drosophila postembryonic nervous system development: a model for the endocrine control of development.Genetics · 2023Review
- Article
- Patient-associated mutations in Drosophila Alk perturb neuronal differentiation and promote survival.Disease models & mechanisms · 2022Article
- Dynamic extrinsic pacing of the HOX clock in human axial progenitors controls motor neuron subtype specification.Development (Cambridge, England) · 2021Article
- Transporter-mediated ecdysteroid trafficking across cell membranes: A novel target for insect growth regulators.Journal of pesticide science · 2021Article
- Steroid hormones, dietary nutrients, and temporal progression of neurogenesis.Current opinion in insect science · 2021Review
- Emerging Roles of Single-Cell Multi-Omics in Studying Developmental Temporal Patterning.International journal of molecular sciences · 2020Review
- A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells.Science advances · 2020Article
- Article
- The Temporal Neurogenesis Patterning of Spinal p3-V3 Interneurons into Divergent Subpopulation Assemblies.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Steroid Hormone Entry into the Brain Requires a Membrane Transporter in Drosophila.Current biology : CB · 2020Article
- HLH-2/E2A Expression Links Stochastic and Deterministic Elements of a Cell Fate Decision during C. elegans Gonadogenesis.Current biology : CB · 2019Article
- The development and assembly of the Drosophila adult ventral nerve cord.Current opinion in neurobiology · 2019Review
- Timing the spinal cord development with neural progenitor cells losing their proliferative capacity: a theoretical analysis.Neural development · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
During neurogenesis, vertebrate and Drosophila progenitors change over time as they generate a diverse population of neurons and glia. Vertebrate neural progenitors have long been known to use both progenitor-intrinsic and progenitor-extrinsic cues to regulate temporal patterning. In contrast, virtually all temporal patterning mechanisms discovered in Drosophila neural progenitors (neuroblasts) involve progenitor-intrinsic temporal transcription factor cascades. Recent results, however, have revealed several extrinsic pathways that regulate Drosophila neuroblast temporal patterning: nutritional cues regulate the timing of neuroblast proliferation/quiescence and a steroid hormone cue that is required for temporal transcription factor expression. Here, we discuss newly discovered extrinsic cues regulating neural progenitor temporal identity in Drosophila, highlight conserved mechanisms, and raise open questions for the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.