Evidence map›Paper›PMID 28903922›Full record

SynthesisBMJ (Clinical research ed.)2017

Risk of relapse after antidepressant discontinuation in anxiety disorders, obsessive-compulsive disorder, and post-traumatic stress disorder: systematic review and meta-analysis of relapse prevention trials.

Neeltje M Batelaan, Renske C Bosman, Anna Muntingh, Willemijn D Scholten, Klaas M Huijbregts, Anton J L M van Balkom

Erratum issued Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMJ (Clinical research ed.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06134323 (Efficacy and Mechanism of Transcutaneous Vagus Nerve Stimulation in the Treatment of Generalized Anxiety Disorder), which is not on this map. Cited by 60 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06134323 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Efficacy and Mechanism of Transcutaneous Vagus Nerve Stimulation in the Treatment of Generalized Anxiety Disorder

TypeinterventionalSponsorXijing HospitalRan2023 to 2025Enrolled82ConditionsGeneralized Anxiety DisorderArmsmedication-combined transcutaneous vagus nerve stimulation, medication-combined sham stimulation
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Trial
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  14. Article
  15. Managing anxiety-related disorders from pregnancy to parenthood.Archives of gynecology and obstetrics · 2026
    Review
  16. Article
  17. Article
  18. Socioeconomic status, antidepressant use, and return to work after disability due to common mental disorders.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Neeltje M BatelaanDepartment of Psychiatry and Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center Amsterdam, Amsterdam, Netherlands n.batelaan@ggzingeest.nl.
Renske C BosmanDepartment of Psychiatry and Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center Amsterdam, Amsterdam, Netherlands.
Anna MuntinghDepartment of Psychiatry and Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center Amsterdam, Amsterdam, Netherlands.
Willemijn D ScholtenDepartment of Psychiatry and Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center Amsterdam, Amsterdam, Netherlands.
Klaas M HuijbregtsDepartment of Psychiatry and Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center Amsterdam, Amsterdam, Netherlands.
Anton J L M van BalkomDepartment of Psychiatry and Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, VU University Medical Center Amsterdam, Amsterdam, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Withholding TreatmentAntidepressive AgentsAnxiety DisordersFemaleHumansMaleObsessive-Compulsive DisorderRandomized Controlled Trials as TopicRecurrenceRisk FactorsSecondary PreventionStress Disorders, Post-TraumaticTime FactorsAntidepressive Agents

Identifiers

PMID28903922
PMCPMC5596392

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.