Evidence map›Paper›PMID 28904196›Full record

ArticleJournal of virology2017

Vaccinia Virus Encodes a Novel Inhibitor of Apoptosis That Associates with the Apoptosome.

Melissa R Ryerson, Monique M Richards, Marc Kvansakul, Christine J Hawkins, Joanna L Shisler

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  4. Review
  5. Infection and immunity · 2024
    Article
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  13. Review
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  15. Contribution of yeast models to virus research.Applied microbiology and biotechnology · 2021
    Review
  16. Article
  17. Review
  18. Poxviral Strategies to Overcome Host Cell Apoptosis.Pathogens (Basel, Switzerland) · 2020
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Melissa R RyersonDepartment of Microbiology, University of Illinois, Urbana, Illinois, USA.
Monique M RichardsDepartment of Microbiology, University of Illinois, Urbana, Illinois, USA.
Marc KvansakulDepartment of Biochemistry and Genetics, La Trobe University, Melbourne, Australia.ORCID http://orcid.org/0000-0003-2639-2498
Christine J HawkinsDepartment of Biochemistry and Genetics, La Trobe University, Melbourne, Australia.
Joanna L ShislerDepartment of Microbiology, University of Illinois, Urbana, Illinois, USA jshisler@illinois.edu.ORCID http://orcid.org/0000-0003-4833-1557
University of Illinois Urbana-Champaign · USLa Trobe University · AU

Funding

Infection Biology Training GrantT32AI078876 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SLAUCH, JAMES M. · 2010 to 2014
$892k
New Approaches toward cultivating Molluscumm contagiosum virusR21AI117105 · NIAID · UNIVERSITY OF ROCHESTER · PI WARD, BRIAN M · 2016 to 2017
$424k
NIAID NIH HHS R21 AI117105NIAID NIH HHS T32 AI078876
6 · The paper itself

Abstract

Apoptosis is an important antiviral host defense mechanism. Here we report the identification of a novel apoptosis inhibitor encoded by the vaccinia virus (VACV)

Indexed as

ApoptosisAnimalsAnkyrin RepeatApoptosis Regulatory ProteinsApoptosomesApoptotic Protease-Activating Factor 1Caspase 9HeLa CellsHost-Pathogen InteractionsHumansJurkat CellsSaccharomyces cerevisiaeStaurosporineVaccinia virusAPAF1 protein, humanApoptosis Regulatory ProteinsApoptosomesApoptotic Protease-Activating Factor 1Caspase 9Staurosporineankyrin repeatApaf-1apoptosisapoptosomecaspase-9M1Lpoxvirusvaccinia virus

Identifiers

PMID28904196
PMCPMC5686757
OpenAlexW2754181610

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.