ArticleJournal of food and drug analysis2014
Antioxidant effects of Camellia sinensis L. extract in patients with type 2 diabetes.
Article in Journal of food and drug analysis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Effects of green tea supplementation on antioxidant status and inflammatory markers in adults: a grade-assessed systematic review and dose-response meta-analysis of randomised controlled trials.Journal of nutritional science · 2025Pooled it
- The Pharmacological Activity ofBiomolecules · 2020Pooled it
- Trial
- Phytochemical Insights and Industrial Applications ofNutrients · 2025Review
- Biosynthesis and Characterization of Silver Nanoparticles from the Extremophile PlantNanomaterials (Basel, Switzerland) · 2022Article
- Review
- Monoterpenoid Glycosides from the Leaves ofMolecules (Basel, Switzerland) · 2022Article
- Article
- Effect of Green Tea Supplementation on Antioxidant Status in Adults: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Antioxidants (Basel, Switzerland) · 2021Review
- Update of green tea interactions with cardiovascular drugs and putative mechanisms.Journal of food and drug analysis · 2018Review
- Extraction optimization of gallic acid, (+)-catechin, procyanidin-B2, (-)-epicatechin, (-)-epigallocatechin gallate, and (-)-epicatechin gallate: their simultaneous identification and quantification in Saraca asoca.Journal of food and drug analysis · 2017Article
- Antidiabetic Effects of Tea.Molecules (Basel, Switzerland) · 2017Review
- Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose.Journal of food and drug analysis · 2016Article
- Inhibitory effects of polyphenol-enriched extract from Ziyang tea against human breast cancer MCF-7 cells through reactive oxygen species-dependent mitochondria molecular mechanism.Journal of food and drug analysis · 2016Article
- Antioxidant and antidiabetic activities of 11 herbal plants from Hyrcania region, Iran.Journal of food and drug analysis · 2016Article
- Effect of storage time on metabolite profile and alpha-glucosidase inhibitory activity of Cosmos caudatus leaves - GCMS based metabolomics approach.Journal of food and drug analysis · 2015Article
- Synergisms in Alpha-glucosidase Inhibition and Antioxidant Activity ofPharmacognosy researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of diabetes mellitus (DM) has dramatically increased in the past decade. Furthermore, increasing evidence from research shows that oxidative stress (OS) plays a crucial role in the pathogenesis of diabetes and in its complications. A search for ways to reduce oxidative damage has become the focus of interest for the majority of scientists. In this study, we determined the radical scavenging activity of single green tea constituents by using an on-line high performance liquid chromatography (HPLC)-2,2-diphenyl-1-picrylhydrazyl (DPPH) method and evaluated the antioxidant effects on type 2 diabetic patients by performing a double-blind, placebo-controlled study. Epigallocatechin gallate was identified as the most potent antioxidant, contributing approximately 50% of the total antioxidant capacity of green tea extract. We also found a statistically significant decrement of lipid peroxidation markers in patients treated with green tea extract after 9 months or after 18 months of follow-up. Overall, these findings are attractive for diabetic patients, helping them to keep a high level of performance and well-being, which ultimately may delay the time of disability and reduce mortality.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.