Evidence map›Paper›PMID 28911558›Full record

ArticleJournal of food and drug analysis2016

Inhibitory effects of polyphenol-enriched extract from Ziyang tea against human breast cancer MCF-7 cells through reactive oxygen species-dependent mitochondria molecular mechanism.

Wenfeng Li, Nianwu He, Lingmin Tian, Xiaolong Shi, Xingbin Yang

Open access · hybridAbstract read
In one paragraph

Article in Journal of food and drug analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

  1. Polyphenol-enriched fraction ofFrontiers in pharmacology · 2026
    Article
  2. International journal of molecular sciences · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Wenfeng LiKey Laboratory of Ministry of Education for Medicinal Resource and Natural Pharmaceutical Chemistry, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, China.
Nianwu HeCollege of Biopharmaceutical and Food Engineering, Shangluo University, Shangluo, China.
Lingmin TianKey Laboratory of Ministry of Education for Medicinal Resource and Natural Pharmaceutical Chemistry, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, China.
Xiaolong ShiKey Laboratory of Ministry of Education for Medicinal Resource and Natural Pharmaceutical Chemistry, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, China.
Xingbin YangKey Laboratory of Ministry of Education for Medicinal Resource and Natural Pharmaceutical Chemistry, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an, China.
Shaanxi Normal University · CNShangluo University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A polyphenol-enriched extract from selenium-enriched Ziyang green tea (ZTP) was selected to evaluate its antitumor effects against human breast cancer MCF-7 cells. In ZTP, (-)-epigallocatechin gallate (28.2%) was identified as the major catechin, followed by (-)-epigallocatechin (5.7%) and (-)-epicatechin gallate (12.6%). ZTP was shown to inhibit MCF-7 cell proliferation (half maximal inhibitory concentration, IC

Indexed as

TeaBreast NeoplasmsHumansMCF-7 CellsMitochondriaReactive Oxygen SpeciesReactive Oxygen SpeciesTeaapoptosisbreast cancerMCF-7 cellspolyphenolsZiyang green tea

Identifiers

PMID28911558
PMCPMC9336659
OpenAlexW2284493870

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.