ArticleJournal of food and drug analysis2016
Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose.
Article in Journal of food and drug analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
75 citing papers in PubMed, 1 synthesis or guideline pooled it, 227 citations in OpenAlex.
- The effect of Sumac on cardiometabolic parameters in adults: a systematic review and meta-analysis of randomized controlled trials.Frontiers in nutrition · 2024Pooled it
- Ethnopharmacological insights into type 2 diabetes management by traditional Moroccan herbal teas: HPLC-MS characterization of phenolic compounds and their related antioxidant and enzyme inhibitory activities.BMC complementary medicine and therapies · 2026Article
- Comparative Analysis of Chemical Composition and Bioactivities of Essential Oils From Different Parts of Wild-Grown Alpinia siamensis K.Schum. in Vietnam.Chemistry & biodiversity · 2026Article
- Effects of Household Cooking Methods on the Nutritional, Phytochemical and Functional Properties ofMolecules (Basel, Switzerland) · 2026Article
- Comprehensive Chemical and Biological Evaluation ofFood science & nutrition · 2026Article
- The Evolving Therapeutic Landscape of Gallic Acid: A Review of Mechanistic Insights and Clinical Potential.Molecular nutrition & food research · 2026Review
- Protective effects of Fraxinus xanthoxyloides bark in alloxan-induced diabetic rats: A phytochemical and pharmacological approach.PloS one · 2026Article
- Synergistic enzyme action boosts phenolic compounds in flaxseed during germination using a two-level factorial design.Scientific reports · 2025Article
- Chemical analysis, antihyperglycemic properties and enzyme inhibition ofJournal of pharmaceutical analysis · 2025Article
- Sustainable Synthesis of 1,2-Disubstituted Benzimidazoles as Promising α-Glucosidase Inhibitors: In Vitro and In Silico Evaluation.Pharmaceuticals (Basel, Switzerland) · 2025Article
- A Comparative Study of the Phytochemical Composition, Antioxidant Properties, and In Vitro Anti-Diabetic Efficacy of Different Extracts ofMarine drugs · 2025Article
- Metabolic Syndrome Prevention Potential of Tamarillo: Phytochemical Composition, Antioxidant Activity, and Enzyme Inhibition Before and After Digestion.Foods (Basel, Switzerland) · 2025Article
- A novel Enterococcus durans with antimicrobial, anti-diabetes and anti-alzheimer activities isolated from Egypt.AMB Express · 2025Article
- Unlocking nature's antidiabetic potential: computer-aided discovery of α-amylase and α-glucosidase inhibitors inIn silico pharmacology · 2025Article
- Parkia biglobosa Jacq. (Locust Bean) leaves and seeds extracts attenuates diabetic-linked cognitive dysfunction in streptozotocin-induced male wistar rats.Metabolic brain disease · 2024Article
- Article
- Thiazolidine-2,4-dione hybrids as dual alpha-amylase and alpha-glucosidase inhibitors: design, synthesis,RSC medicinal chemistry · 2024Article
- Development and Evaluation of Bioconverted Milk with Anti-Microbial Effect against Periodontal Pathogens and α-Glucosidase Inhibitory Activity.Microorganisms · 2024Article
- Metabolite Profiling and Biological Activity Assessment ofInternational journal of molecular sciences · 2024Article
- New Garden Rose (Plants (Basel, Switzerland) · 2024Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acarbose is an antidiabetic drug which acts by inhibiting α-amylase and α-glucosidase activities but with deleterious side effects. Gallic acid (GA) is a phenolic acid that is widespread in plant foods. We therefore investigated the influence of GA on α-amylase and α-glucosidase inhibitory properties of acarbose (in vitro). Aqueous solutions of acarbose and GA were prepared to a final concentration of 25μM each. Thereafter, mixtures of the samples (50% acarbose + 50% GA; 75% acarbose+25% GA; and 25% acarbose+75% GA) were prepared. The results revealed that the combination of 50% acarbose and 50% GA showed the highest α-glucosidase inhibitory effect, while 75% acarbose+25% GA showed the highest α-amylase inhibitory effect. Furthermore, all the samples caused the inhibition of Fe
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.