Evidence mapPaperPMID 28913629Full record

Observational studyWiener klinische Wochenschrift2017

Atherogenic index of plasma is positively associated with the risk of all-cause death in elderly women : A 10-year follow-up.

Matej Bendzala, Peter Sabaka, Martin Caprnda, Andrea Komornikova, Maria Bisahova, Ruth Baneszova, Daniel Petrovic, Robert Prosecky, Luis Rodrigo, Peter Kruzliak and 1 more

Open access · greenAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Wiener klinische Wochenschrift, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Atherogenic index of plasma: A valuable novel index to distinguish patients with unstable atherogenic plaques.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022
    Article
  16. Observational
  17. Article
  18. Journal of diabetes and metabolic disorders · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Matej Bendzala1st Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Peter Sabaka1st Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Martin Caprnda1st Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Andrea Komornikova1st Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Maria Bisahova1st Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Ruth Baneszova1st Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
Daniel PetrovicFaculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Robert ProseckyDepartment of Internal Medicine, Brothers of Mercy Hospital, Brno, Czech Republic.
Luis RodrigoFaculty of Medicine, University of Oviedo, Central University Hospital of Asturias (HUCA), Oviedo, Spain.
Peter KruzliakDepartment of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences, Palackeho tr. 1/1946, 612 42, Brno, Czech Republic. kruzliakpeter@gmail.com.ORCID http://orcid.org/0000-0002-7069-3784
Andrej Dukat1st Department of Internal Medicine, Faculty of Medicine, Comenius University and University Hospital, Bratislava, Slovakia.
University Hospital Bratislava · SKUniversidad de Oviedo · ESUniversity of Ljubljana · SIUniversity of Veterinary Sciences Brno · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe blood concentrations of total cholesterol and low-density lipoprotein (LDL) do not predict survival in patients older than 60 years. The atherogenic index of plasma (AIP) is a logarithm of the triacylglycerol to high-density lipoprotein (HDL) ratio and a surrogate for the concentration of small dense LDL. It might be a better reflection of the risk of all-cause death in elderly patients.

methodsWe conducted a prospective observational study of patients with arterial hypertension older than 60 years. The concentrations of total cholesterol, LDL, HDL and triacylglycerol were measured at the time of the recruitment and the patients were observed for 10 years. Cox regression analysis was performed to assess the effects of lipoproteins and AIP on survival.

resultsA total of 500 patients were recruited and 473 of them (226 men, 247 women) either died or successfully completed the 10-year follow-up and were included in the analysis. The AIP was positively associated, while HDL concentration was negatively associated with the risk of all-cause death adjusted for age, smoking habits, statin use, history of diabetes mellitus, myocardial infarction, stroke and peripheral artery occlusive disease (PAOD) in elderly women but not in men. The LDL, total cholesterol, triacylglycerol and non-HDL concentrations were not associated with the risk of death in both sexes.

conclusionsThe AIP is positively associated with the risk of all-cause death in elderly women with arterial hypertension independent of age, smoking habits, statin therapy and comorbidities.

Indexed as

AgedAlgorithmsAtherosclerosisCholesterolCholesterol, LDLFemaleHumansHypertensionLipoproteins, HDLLipoproteins, LDLMiddle AgedProspective StudiesSlovakiaTriglyceridesCholesterolCholesterol, LDLLipoproteins, HDLLipoproteins, LDLTriglyceridesAtherogenic indexElderly populationHDLLDLRisk of mortality

Identifiers

PMID28913629
OpenAlexW2755154564

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.