ArticleJournal of the International Neuropsychological Society : JINS2018
Relationship between Cognitive Performance and Measures of Neurodegeneration among Hispanic and White Non-Hispanic Individuals with Normal Cognition, Mild Cognitive Impairment, and Dementia.
Article in Journal of the International Neuropsychological Society : JINS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Two-Year Longitudinal Outcomes of Subjective Cognitive Decline in Hispanics Compared to Non-hispanic Whites.Journal of geriatric psychiatry and neurology · 2025Article
- Ensuring Fairness in Detecting Mild Cognitive Impairment with MRI.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024Article
- Characterizing age- and sex-related differences in brain structure among middle-aged and older Hispanic/Latino adults in the study of Latinos- investigation of neurocognitive aging magnetic resonance imaging (SOL-INCA MRI).Neurobiology of aging · 2023Article
- CT-Detected MTA Score Related to Disability and Behavior in Older People with Cognitive Impairment.Biomedicines · 2022Article
- Neurodegeneration from the AT(N) framework is different among Mexican Americans compared to non-Hispanic Whites: A Health & Aging Brain among Latino Elders (HABLE) Study.Alzheimer's & dementia (Amsterdam, Netherlands) · 2022Article
- Culture, Ethnicity, and Level of Education in Alzheimer's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Review
- Self-reported subjective cognitive decline is associated with global cognition in a community sample of Latinos/as/x living in the United States.Journal of clinical and experimental neuropsychology · 2021Article
- Differences in Alzheimer's Disease and Related Dementias Pathology Among African American and Hispanic Women: A Qualitative Literature Review of Biomarker Studies.Frontiers in systems neuroscience · 2021Review
- Ethnoracial Differences in Lewy Body Diseases with Cognitive Impairment.Journal of Alzheimer's disease : JAD · 2020Article
- Types of errors on a semantic interference task in mild cognitive impairment and dementia.Neuropsychology · 2019Article
- Dementia-Related Neuropsychological Testing Considerations in Non-Hispanic White and Latino/Hispanic Populations.Psychology & neuroscience · 2019Article
- Origins Matter: Culture Impacts Cognitive Testing in Parkinson's Disease.Frontiers in human neuroscience · 2019Article
- Medial temporal lobe atrophy and posterior atrophy scales normative values.NeuroImage. Clinical · 2019Article
- [Effect of intrahippocampal injection of anti-cellular prion protein monoclonal antibody on cognitive deficits in APPswe/PSEN1Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018Article
- Cultural factors related to neuropsychological performance and brain atrophy among Hispanic older adults with amnestic Mild Cognitive Impairment (aMCI): A pilot study.Applied neuropsychology. AdultArticle
- Racial/ethnic differences in neuropsychological test performance in frontotemporal degeneration.Alzheimer's & dementia (Amsterdam, Netherlands)Article
- Functional measures and AD biomarkers among Hispanic and White non-Hispanic older adults.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
objectivesThe aim of this study was to determine the presence and severity of potential cultural and language bias in widely used cognitive and other assessment instruments, using structural MRI measures of neurodegeneration as biomarkers of disease stage and severity.
methodsHispanic (n=75) and White non-Hispanic (WNH) (n=90) subjects were classified as cognitively normal (CN), amnestic mild cognitive impairment (aMCI) and mild dementia. Performance on the culture-fair and educationally fair Fuld Object Memory Evaluation (FOME) and Clinical Dementia Rating Scale (CDR) between Hispanics and WNHs was equivalent, in each diagnostic group. Volumetric and visually rated measures of the hippocampus entorhinal cortex, and inferior lateral ventricles (ILV) were measured on structural MRI scans for all subjects. A series of analyses of covariance, controlling for age, depression, and education, were conducted to compare the level of neurodegeneration on these MRI measures between Hispanics and WNHs in each diagnostic group.
resultsAmong both Hispanics and WNH groups there was a progressive decrease in volume of the hippocampus and entorhinal cortex, and an increase in volume of the ILV (indicating increasing atrophy in the regions surrounding the ILV) from CN to aMCI to mild dementia. For equivalent levels of performance on the FOME and CDR, WNHs had greater levels of neurodegeneration than did Hispanic subjects.
conclusionsAtrophy in medial temporal regions was found to be greater among WNH than Hispanic diagnostic groups, despite the lack of statistical differences in cognitive performance between these two ethnic groups. Presumably, unmeasured factors result in better cognitive performance among WNH than Hispanics for a given level of neurodegeneration. (JINS, 2018, 24, 176-187).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.