Evidence map›Paper›PMID 28924010›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

MicroRNA-1906, a Novel Regulator of Toll-Like Receptor 4, Ameliorates Ischemic Injury after Experimental Stroke in Mice.

Xiaomeng Xu, Zhuoyu Wen, Nan Zhao, Xiaohui Xu, Fang Wang, Jie Gao, Yongjun Jiang, Xinfeng Liu

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Advancing Ischemic Stroke Prognosis: Key Role of MiR-155 Non-Coding RNA.International journal of molecular sciences · 2025
    Review
  4. Article
  5. Review
  6. MicroRNA Profiles in Critically Ill Patients.Current medicinal chemistry · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Regulation of blood-brain barrier integrity by microglia in health and disease: A therapeutic opportunity.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Review
  18. Microglial Density Alters Measures of Axonal Integrity and Structural Connectivity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xiaomeng XuDepartment of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China and.ORCID 0000-0002-1717-538X
Zhuoyu WenDepartment of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China and.
Nan ZhaoDepartment of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China and.ORCID 0000-0002-6909-4047
Xiaohui XuDepartment of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China and.
Fang WangDepartment of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China and.
Jie GaoDepartment of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China and.
Yongjun JiangDepartment of Neurology, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China Jiangyjnju@gmail.com xfliu2@vip.163.com.
Xinfeng LiuDepartment of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China and Jiangyjnju@gmail.com xfliu2@vip.163.com.ORCID 0000-0002-8182-9632
Nanjing General Hospital of Nanjing Military Command · CNSecond Affiliated Hospital of Guangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toll-like receptor 4 (TLR4) is a proinflammatory cascade initiator in poststroke inflammation. In this study, miR-1906, a novel regulator of TLR4, was identified via

Indexed as

AnimalsBrain IschemiaCells, CulturedFemaleMaleMiceMice, Inbred C57BLMice, KnockoutMicroRNAsPregnancyStrokeToll-Like Receptor 4MicroRNAsTlr4 protein, mouseToll-Like Receptor 4cerebrovascular diseaseinflammationmicroRNAstrokeToll like receptor 4

Identifiers

PMID28924010
PMCPMC6596627
OpenAlexW2755413029

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.