Evidence map›Paper›PMID 28924040›Full record

ArticleThe Journal of biological chemistry2017

A B-Z junction induced by an A … A mismatch in GAC repeats in the gene for cartilage oligomeric matrix protein promotes binding with the hZα

Narendar Kolimi, Yogeeshwar Ajjugal, Thenmalarchelvi Rathinavelan

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
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  7. Article
  8. Z-DNA and Z-RNA in human disease.Communications biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Narendar KolimiFrom the Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India.
Yogeeshwar AjjugalFrom the Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India.
Thenmalarchelvi RathinavelanFrom the Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana State 502285, India tr@iith.ac.in.
Indian Institute of Technology Hyderabad · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GAC repeat expansion from five to seven in the exonic region of the gene for cartilage oligomeric matrix protein (COMP) leads to pseudoachondroplasia, a skeletal abnormality. However, the molecular mechanism by which GAC expansions in the

Indexed as

Trinucleotide RepeatsAchondroplasiaAdenosine DeaminaseBase Pair MismatchCartilage Oligomeric Matrix ProteinDNA, B-FormDNA, Z-FormHumansMolecular Dynamics SimulationNucleic Acid ConformationProtein BindingProtein DomainsRNA-Binding ProteinsRNA EditingADAR protein, humanAdenosine DeaminaseCartilage Oligomeric Matrix ProteinDNA, B-FormDNA, Z-FormRNA-Binding ProteinsTSP5 protein, humancartilage oligomeric matrix proteinCDhuman adar1 proteinmolecular dynamicsNMRpseudoachdroplasiaRNA editingtrinucleotide repeat disease

Identifiers

PMID28924040
PMCPMC5704460
OpenAlexW2755438143

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.