ArticleNutrients2017
Anti-Diabetic Effects of Phenolic Extract from Rambutan Peels (Nephelium lappaceum) in High-Fat Diet and Streptozotocin-Induced Diabetic Mice.
Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 72 citations in OpenAlex.
- Deep eutectic solvent extraction and AB-8 resin adsorption for rambutan shell polyphenol: Profiling and bioactivity assessments.Food chemistry: X · 2026Article
- Metabolic fate of rambutan (Food chemistry: X · 2026Article
- Nutritional, pharmaceutical, and functional aspects of rambutan in industrial perspective: An updated review.Food science & nutrition · 2023Review
- Article
- Article
- Effect of induced diabetes on morphometric indexes of the cerebellar cortex and gene expression in C57BL mice.Iranian journal of basic medical sciences · 2023Article
- Review
- Protective Mechanism ofFrontiers in nutrition · 2022Article
- Phytochemical Investigation and Therapeutical Potential ofOxidative medicine and cellular longevity · 2022Article
- Review ofMolecules (Basel, Switzerland) · 2021Review
- Microencapsulation of Rambutan Peel Extract by Spray Drying.Foods (Basel, Switzerland) · 2020Article
- Effects of Rambutan Peel (Nutrients · 2020Article
- Antidiabetic and Antioxidative Potential of the Blue Congo Variety of Purple Potato Extract in Streptozotocin-Induced Diabetic Rats.Molecules (Basel, Switzerland) · 2019Article
- Effects of citral on oxidative stress and hepatic key enzymes of glucose metabolism in streptozotocin/high-fat-diet induced diabetic dyslipidemic rats.Iranian journal of basic medical sciences · 2019Article
- Phytochemical analysis and antidiabetic potential of Elaeagnus umbellata (Thunb.) in streptozotocin-induced diabetic rats: pharmacological and computational approach.BMC complementary and alternative medicine · 2018Article
- Metal Chelating, Inhibitory DNA Damage, and Anti-Inflammatory Activities of Phenolics from Rambutan (Molecules (Basel, Switzerland) · 2018Article
- Effects of Polyphenol-Rich Foods on Human Health.Nutrients · 2018Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies have shown that rambutan peel phenolic (RPP) extract demonstrate high antioxidant and antiglycation activities in vitro and in vivo. This study further evaluated the anti-diabetic activity of RPP in a mouse model of Type II diabetes induced by streptozotocin combined with high-fat diet. Results showed that RPP increased the body weight and reduced the fasting blood glucose level of the diabetic mice. RPP significantly reduced the serum levels of total cholesterol, triglyceride, creatinine, and glycated serum protein in diabetic mice in a dose-dependent manner. Glycogen content in mice liver was recovered by RPP, which further increased the activity of superoxide dismutase and glutathione peroxidase and reduced lipid peroxidation in diabetic mice. Histological analysis showed that RPP effectively protected the tissue structure of the liver, kidney, and pancreas. In addition, RPP decreased the mesangial index and inhibited the expression of TGF-β in the kidney of diabetic mice.
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Registered trials
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